SDS
CofA
*Please inquire the availability for this product. Dehydrocurvularin is a 12-membered macrocyclic lactone incorporating a resorcinyl moiety, produced by a number of fungal species including Curvularia, Penicillium and Alternaria. Dehydrocurvularin inhibits cell division by disrupting mitotic spindle formation and acts as a developmental regulator by inhibiting self-sporulation in Alternaria alternata. More recently dehydrocurvularin has been shown to have antimalarial activity.
More Information
Alternate Name/Synonyms
α,β-Dehydrocurvularin
SKU
D-2479
CAS #
1095588-70-7
Chemical Formula
C16H18O5
Molecular Weight
290.3
Appearance
White solid
Purity
>98% by HPLC
Solubility
Soluble in methanol, ethanol, DMF, DMSO, and limited water solubility
Storage Temp
-20°C
THERAPEUTIC AREA
Infectious Diseases
USE
An inhibitor of cell division shown to have antimalarial activity.
INCHI
InChI=1S/C16H18O5/c1-10-5-3-2-4-6-13(18)16-11(8-15(20)21-10)7-12(17)9-14(16)19/h4,6-7,9-10,17,19H,2-3,5,8H2,1H3/b6-4+/t10-/m0/s1
SMILES
C[C@H]1CCC/C=C/C(=O)C2=C(C=C(C=C2CC(=O)O1)O)O
