10-Hydroxycamptothecin

SKU
H-1132
  • CAS:64439-81-2
  • Formula:C20H16N2O5
  • MW:364.4 Da
  • Appearance:Pale yellow solid
  • Purity:≥97%

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Product Name Qty
10-Hydroxycamptothecin
100 mg
$335.02

Description

10-Hydroxycamptothecin a DNA topoisomerase I inhibitor. It induces apoptosis in human breast cancer cells.

More Information
Alternate Name/Synonyms
(+/-)-10-Hydroxycamptothecin; Hydroxy camptothecine
SKU
H-1132
CAS #
64439-81-2
Chemical Name
19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione
Chemical Formula
C20H16N2O5
Molecular Weight
364.4 Da
Appearance
Pale yellow solid
Purity
≥97%
Solubility
Soluble in DMSO
Melting Point
272°C
Preparation
N/A
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
A DNA topoisomerase I inhibitor. It induces apoptosis in human breast cancer cells.
Merck Index
N/A
MDL NUMBER
MFCD00189425
CHEMACX
X7328106-8
INCHI
InChI=1S/C20H16N2O5/c1-2-20(26)13-7-15-17-10(6-11-14(21-17)4-3-5-16(11)23)8-22(15)18(24)12(13)9-27-19(20)25/h3-7,23,26H,2,8-9H2,1H3/t20-/m0/s1
SMILES
CC[C@@]1(c2cc-3n(c(=O)c2COC1=O)Cc4c3nc5cccc(c5c4)O)O
Peptide sequence
N/A
RTECS
N/A
UN #'S
N/A
PACKING GROUP
N/A
HAZARD CLASS
N/A
Handling
Avoid contact with skin, eyes, and personal clothing. Wash hands thoroughly after handling. Avoid breathing fumes. Use only with adequate ventilation. Wear suitable protective clothing, gloves, and eye/face protection. Keep away from sources of ignition. Minimize dust generation and accumulation. Keep container tightly closed. Open and handle container with care. Do not eat, drink, or smoke while handling.
Certificate of Analysis 1
Certificate of Analysis 2
GHS PICTOGRAMS
Handling Avoid contact with skin, eyes, and personal clothing. Wash hands thoroughly after handling. Avoid breathing fumes. Use only with adequate ventilation. Wear suitable protective clothing, gloves, and eye/face protection. Keep away from sources of ignition. Minimize dust generation and accumulation. Keep container tightly closed. Open and handle container with care. Do not eat, drink, or smoke while handling.
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