10z-Hymenialdisine

SKU
H-1150
  • CAS:82005-12-7
  • Formula:C11H10BrN5O2
  • MW:324.1
  • Appearance:Yellow powder
  • Purity:≥97%

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Product Name Qty
10z-Hymenialdisine
500 ug
$241.02
10z-Hymenialdisine
1 mg
$415.76

Description

10z-Hymenialdisine is a potent inhibitor of mitogen-activated protein kinase kinase-1, It acts as an Inhibitor of G2 DNA damage checkpoint and cyclin-dependent kinases CDK1/cyclin B and CDK2/cyclin E glycogen synthase kinase-b.

Isolated from Axinella carteri.

 

Not for human therapeutic use or for medicinal purposes. For research applications only.

More Information
Alternate Name/Synonyms
Hymenialdisine; (Z)-Hymenialdisine; 4-(2-Amino-4-oxo-2-imidazolidin-5-ylidene)-2-bromo-4,5,6,7-tetrahydropyrrolo[2,3-c]azepin-8-one
SKU
H-1150
CAS #
82005-12-7
Chemical Name
(4Z)-4-(2-amino-5-oxo-1H-imidazol-4-ylidene)-2-bromo-1,5,6,7-tetrahydropyrrolo[2,3-c]azepin-8-one
Chemical Formula
C11H10BrN5O2
Molecular Weight
324.1
Appearance
Yellow powder
Purity
≥97%
Solubility
Soluble in DMSO (25 mg/mL) or Ethanol
Melting Point
273.54°C
Storage Temp
-20°C
THERAPEUTIC AREA
Neurological Disorders
USE
An ATP competitive, CK1 and GSK-3β inhibitor in Alzheimer’s disease
MDL NUMBER
MFCD04037007
CHEMACX
X1461558-2
INCHI
InChI=1S/C11H10BrN5O2/c12-6-3-5-4(7-10(19)17-11(13)16-7)1-2-14-9(18)8(5)15-6/h3,15H,1-2H2,(H,14,18)(H3,13,16,17,19)/b7-4-
SMILES
c1c2c([nH]c1Br)C(=O)NCC/C2=C/3C(=O)N=C(N3)N
RTECS
UY8427710
UN #'S
UN 2811
PACKING GROUP
III
Handling
Keep cool and dry. Store under inert gas. Protect from light.
Certificate of Analysis 1
GHS PICTOGRAMS
Handling Keep cool and dry. Store under inert gas. Protect from light.
UN #'S UN 2811
Packing Group III
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