2-Chloro-4-nitrophenyl a-L-fucopyranoside

SKU
C-2913
  • CAS:157843-41-9
  • Formula:C12H14CINO7
  • MW:319.69
  • Appearance:White to pale yellow powder
  • Purity: 98%
Product Name Qty
2-Chloro-4-nitrophenyl a-L-fucopyranoside
250mg
$138.14
2-Chloro-4-nitrophenyl a-L-fucopyranoside
500mg
$214.54
2-Chloro-4-nitrophenyl a-L-fucopyranoside
1 g
$413.38

2-Chloro-4-nitrophenyl α-L-fucopyranoside (CNPF) is a substrate for the enzyme α-L-fucosidase (AFU). CNPF is hydrolysed by α-L-fucosidase to fucose and 2-chloro-4-nitrophenol. The levels of AFU in human serum are useful markers for diagnosing hepatocellular carcinoma (HCC), being significantly higher in patients with HCC than those with cirrhosis, other malignant neoplasms or control subjects.  A highly sensitive and specific assay monitoring the hydrolysis of CNPF by AFU has been developed for use in the early diagnosis of HCC.

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