2'-Deoxy-5-fluorocytidine | Irreversible DNA methyl transferase inhibitor

SKU
D-2631
  • CAS:10356-76-0
  • Formula:C9H12FN3O4
  • MW:245.21
  • Appearance:White solid
  • Purity:98% by TLC NMR (Conforms)
Product Name Qty
2'-Deoxy-5-fluorocytidine | Irreversible DNA methyl transferase inhibitor
100 mg
$217.68

2'-Deoxy-5-fluorocytidine is a DNA methyltransferase inhibitor currently in clinical trials for breast cancer and other solid tumors. Like 5'-Azacytidine and decitabine, 2-Deoxy-5-fluorocytidine is a pyrimidine analog that integrates into chromatin to inhibit DNA methylation. It blocks proliferation in colon cancer-derived HCT116 cells by activating DNA response pathways. It inhibits various strains of pathogenic avian influenza viruses in vitro and in vivo.

More Information
Alternate Name/Synonyms
FCDR; NSC-48006; FdCyd
SKU
D-2631
CAS #
10356-76-0
Chemical Name
5-Fluoro-2'deoxycytidine
Chemical Formula
C9H12FN3O4
Molecular Weight
245.21
Appearance
White solid
Purity
98% by TLC NMR (Conforms)
Solubility
Soluble in DMSO (up to 20 mg/ml).
Stability
Stable for 2 years as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Storage Temp
-20°
Hazard Image
Yes
Promo text for AGS discount
N/A
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