- MW:807.1 Da
- Appearance:White Lyophilisate
- Purity:>95% by HPLC
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21-Hydroxyoligomycin A is a rare member of the oligomycin class isolated as a co-metabolite of nemadectin, hence its original naming as nemadectin omega. 21-Hydroxyoligomycin A is structurally distinct and synthesized by a separate pathway from the nemadectins.
Only limited literature references to this metabolite are available. However, in-house testing suggests that 21-hydroxyoligomycin has a more selective action against mammalian tumor cell lines than oligomycin A, exhibiting only weak antifungal and nematocidal activity.
Isolated from Streptomyces sp.
• Structure and Absolute Stereochemistry of 21-Hydroxyoligomycin A. Wagenaar M.M. et al., J Nat Prod. 2007, in
• Plasmid effects on secondary metabolite production by a streptomycete synthesizing an anthelmintic
macrolide.Thomas D.I. et al., J Gen Microbiol. 1991, 137, 2331
Not for human therapeutic use or for medicinal purposes. For research applications only.
|Handling||Handle in accordance with good industrial hygiene and safety practice.|