3-O-Acetyl-11-keto-Beta-boswellic acid, Boswellia serrata

SKU
B-1265
  • CAS:67416-61-9
  • Formula:C32H48O5
  • MW:512.7
  • Appearance:White to off-white Solid
  • Purity:99% by HPLC, NMR

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Product Name Qty
3-O-Acetyl-11-keto-Beta-boswellic acid, Boswellia serrata
5 mg
$165.17

Boswellic acid derivative, which shows anti-tumor and anti-inflammatory activities. Potent non-redox, noncompetitive 5-lipoxygenase and topoisomerase I and IIa inhibitor leading to apoptosis. Mobilizes intracellular Ca2+ and potently inhibits the MAP kinases p38 and p44/42. 10-times more potent than 3-O-Acetyl-boswellic acid. Has been shown to exhibit in vivo efficacy in tumor growth and inhibition.

More Information
SKU
B-1265
CAS #
67416-61-9
Chemical Name
(3R,4R,4AR,6AR,6BS,8AR,11R,12S,12AR,14AR,14BS)-3-ACETYLOXY-4,6A,6B,8A,11,12,14B-HEPTAMETHYL-14-OXO-1,2,3,4A,5,6,7,8,9,10,11,12,12A,14A-TETRADECAHYDROPICENE-4-CARBOXYLIC ACID
Chemical Formula
C32H48O5
Molecular Weight
512.7
Appearance
White to off-white Solid
Purity
99% by HPLC, NMR
Solubility
Soluble in acetone, dichloromethane, diethyl ether or DMSO.
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
Potent non-redox, noncompetitive 5-lipoxygenase and topoisomerase I and IIa inhibitor leading to apoptosis which shows anti-tumor and anti-inflammatory activities
MDL NUMBER
MFCD03788777
CHEMACX
X1618870-0
INCHI
InChI=1S/C32H48O5/c1-18-9-12-28(4)15-16-30(6)21(25(28)19(18)2)17-22(34)26-29(5)13-11-24(37-20(3)33)32(8,27(35)36)23(29)10-14-31(26,30)7/h17-19,23-26H,9-16H2,1-8H3,(H,35,36)/t18-,19+,23-,24-,25+,26-,28-,29+,30-,31-,32-/m1/s1
SMILES
C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC(=O)[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@H]([C@]5(C)C(=O)O)OC(=O)C)C)C)[C@@H]2[C@H]1C)C)C
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Store in Tightly sealed Vial Protect from Light
GHS PICTOGRAMS
Handling Store in Tightly sealed Vial Protect from Light
UN #'S Not Applicable
Packing Group Not Applicable
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