3-O-Acetyl-11-keto-Beta-boswellic acid, Boswellia serrata

SKU
B-1265
  • CAS:67416-61-9
  • Formula:C32H48O5
  • MW:512.7
  • Appearance:White to off-white Solid
  • Purity:99% by HPLC, NMR

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Product Name Qty
3-O-Acetyl-11-keto-Beta-boswellic acid, Boswellia serrata
5 mg
$161.93

Boswellic acid derivative, which shows anti-tumor and anti-inflammatory activities. Potent non-redox, noncompetitive 5-lipoxygenase and topoisomerase I and IIa inhibitor leading to apoptosis. Mobilizes intracellular Ca2+ and potently inhibits the MAP kinases p38 and p44/42. 10-times more potent than 3-O-Acetyl-boswellic acid. Has been shown to exhibit in vivo efficacy in tumor growth and inhibition.

More Information
SKU
B-1265
CAS #
67416-61-9
Chemical Name
(3R,4R,4AR,6AR,6BS,8AR,11R,12S,12AR,14AR,14BS)-3-ACETYLOXY-4,6A,6B,8A,11,12,14B-HEPTAMETHYL-14-OXO-1,2,3,4A,5,6,7,8,9,10,11,12,12A,14A-TETRADECAHYDROPICENE-4-CARBOXYLIC ACID
Chemical Formula
C32H48O5
Molecular Weight
512.7
Appearance
White to off-white Solid
Purity
99% by HPLC, NMR
Solubility
Soluble in acetone, dichloromethane, diethyl ether or DMSO.
Stability
N/A
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
Potent non-redox, noncompetitive 5-lipoxygenase and topoisomerase I and IIa inhibitor leading to apoptosis which shows anti-tumor and anti-inflammatory activities
MDL NUMBER
MFCD03788777
CHEMACX
X1618870-0
INCHI
InChI=1S/C32H48O5/c1-18-9-12-28(4)15-16-30(6)21(25(28)19(18)2)17-22(34)26-29(5)13-11-24(37-20(3)33)32(8,27(35)36)23(29)10-14-31(26,30)7/h17-19,23-26H,9-16H2,1-8H3,(H,35,36)/t18-,19+,23-,24-,25+,26-,28-,29+,30-,31-,32-/m1/s1
SMILES
C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC(=O)[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@H]([C@]5(C)C(=O)O)OC(=O)C)C)C)[C@@H]2[C@H]1C)C)C
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Store in Tightly sealed Vial Protect from Light
Promo text for AGS discount
N/A
GHS PICTOGRAMS
Handling Store in Tightly sealed Vial Protect from Light
UN #'S Not Applicable
Packing Group Not Applicable
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