SDS
CofA
Description
4-Nitrophenyl-2-acetamido-2-deoxy-B-D-galactopyranoside is used a chromogenic substrate for detecting N-acetyl-β-D-galactosaminidase.
Applications
• Substrate for N-acetyl-β-D-galactosaminidase in a spectrophotometric assay and glycosyl hydrolase assays.
• Substrate in β-hexosaminidase assay.
References
• “Lysosomal enzymes are decreased in the kidney of diabetic rats”
• “Loss of a Biofilm-Inhibiting Glycosyl Hydrolase during the Emergence of Yersinia pestis”
Not for human therapeutic use or for medicinal purposes. For research applications only.
More Information
Alternate Name/Synonyms
4-nitrophenyl-2-acetamido-2-deoxygalactopyranoside; GalNAc-beta-PNP
SKU
N-2627
CAS #
14948-96-0
Chemical Name
N-[(2S,3R,4R,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-(4-nitrophenoxy)oxan-3-yl]acetamide
Chemical Formula
C14H18N2O8
Molecular Weight
342.3 Da
Appearance
Light yellow powder
Purity
≥98%
Solubility
Soluble in DMSO and DMFO.
Storage Temp
-20°C
THERAPEUTIC AREA
Not Available
USE
4-Nitrophenyl-2-acetamido-2-deoxy-B-D-galactopyranoside is used as a synthetic substrate in the glycosyl hydrolase assay of Yersinia pseudotuberculosis protein. It is also used as a substrate in -β-hexosaminidase assay in adenocarcinomic human alveolar basal epithelial cells A549, and as a substrate for N-acetyl-β-D-galactosaminidase assay in rat kidney tissue extracts.
Handling
Provide appropriate exhaust ventilation at places where dust is formed. Normal measures for preventive fire protection
| Handling | Provide appropriate exhaust ventilation at places where dust is formed. Normal measures for preventive fire protection |
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