4-Nitrophenyl-2-acetamido-2-deoxy-B-D-galactopyranoside

SKU
N-2627
  • CAS:14948-96-0
  • Formula:C14H18N2O8
  • MW:342.3 Da
  • Appearance:Light yellow powder
  • Purity:≥98%
Product Name Qty
4-Nitrophenyl-2-acetamido-2-deoxy-B-D-galactopyranoside
100 mg
$86.12
4-Nitrophenyl-2-acetamido-2-deoxy-B-D-galactopyranoside
250 mg
$179.44
4-Nitrophenyl-2-acetamido-2-deoxy-B-D-galactopyranoside
1 g
$416.65

Description

4-Nitrophenyl-2-acetamido-2-deoxy-B-D-galactopyranoside is used a chromogenic substrate for detecting N-acetyl-β-D-galactosaminidase.  

 

Applications

• Substrate for N-acetyl-β-D-galactosaminidase in a spectrophotometric assay and glycosyl hydrolase assays.

• Substrate in β-hexosaminidase assay.

 

References

• “Lysosomal enzymes are decreased in the kidney of diabetic rats”

• “Loss of a Biofilm-Inhibiting Glycosyl Hydrolase during the Emergence of Yersinia pestis”

• “Involvement of Lysosomal Exocytosis in the Excretion of Mesoporous Silica Nanoparticles and Enhancement of Drug Delivery Effect by Exocytosis Inhibition”

 

Not for human therapeutic use or for medicinal purposes. For research applications only.

More Information
Alternate Name/Synonyms
4-nitrophenyl-2-acetamido-2-deoxygalactopyranoside; GalNAc-beta-PNP
SKU
N-2627
CAS #
14948-96-0
Chemical Name
N-[(2S,3R,4R,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-(4-nitrophenoxy)oxan-3-yl]acetamide
Chemical Formula
C14H18N2O8
Molecular Weight
342.3 Da
Appearance
Light yellow powder
Purity
≥98%
Solubility
Soluble in DMSO and DMFO.
Storage Temp
-20°C
THERAPEUTIC AREA
Not Available
USE
4-Nitrophenyl-2-acetamido-2-deoxy-B-D-galactopyranoside is used as a synthetic substrate in the glycosyl hydrolase assay of Yersinia pseudotuberculosis protein. It is also used as a substrate in -β-hexosaminidase assay in adenocarcinomic human alveolar basal epithelial cells A549, and as a substrate for N-acetyl-β-D-galactosaminidase assay in rat kidney tissue extracts.
Handling
Provide appropriate exhaust ventilation at places where dust is formed. Normal measures for preventive fire protection
HandlingProvide appropriate exhaust ventilation at places where dust is formed. Normal measures for preventive fire protection
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