5-Aza-2'-deoxycytidine

SKU
A-2171
  • CAS:2353-33-5
  • Formula:C8H12N4O4
  • MW:228.08
  • Appearance:White to off-white Solid
  • Purity:98% by HPLC

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Product Name Qty
5-Aza-2'-deoxycytidine
10 mg
$106.09
5-Aza-2'-deoxycytidine
50 mg
$396.45

An epigenetic modifier. Decitabine is an analogue of the nucleoside 2-deoxycytidine. It is believed to exert its antineoplastic effects after phosphorylation and direct incorporation into DNA and inhibition of DNA methyltransferase, causing hypomethylation of DNA and cellular differentiation or apoptosis. DNA hypomethylation is achieved at concentrations below those required to significantly inhibit DNA synthesis, which may promote restoration of function to genes associated with control of cellular differentiation and proliferation.

More Information
Alternate Name/Synonyms
Decitabine
SKU
A-2171
CAS #
2353-33-5
Chemical Name
4-amino-1-(2-deoxy-β-D-erythro-pentofuranosyl) 1,3,5-triazin-2(1H)-one; Decitabine
Chemical Formula
C8H12N4O4
Molecular Weight
228.08
Appearance
White to off-white Solid
Purity
98% by HPLC
Solubility
DMSO (25 mg/ml), 50% acetic acid (25 mg/ml)
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
It is used as anticancer agent
MDL NUMBER
MFCD00043011
CHEMACX
X1013593-6
INCHI
InChI=1S/C8H12N4O4/c9-7-10-3-12(8(15)11-7)6-1-4(14)5(2-13)16-6/h3-6,13-14H,1-2H2,(H2,9,11,15)/t4-,5+,6+/m0/s1
SMILES
c1nc(nc(=O)n1[C@H]2C[C@@H]([C@H](O2)CO)O)N
Peptide sequence
Not Applicable
RTECS
XZ3012000
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from air and moisture
Certificate of Analysis 1
/media/upload/pdf/A-2171, H1249.pdf
Promo text for AGS discount
N/A
GHS PICTOGRAMS
Handling Protect from air and moisture
UN #'S Not Applicable
Packing Group Not Applicable
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