5-Azacytidine

SKU
A-2172
  • CAS:320-67-2
  • Formula:C8H12N4O5
  • MW:244.3 g/mol
  • Appearance:White to off-white Solid
  • Purity:98% by TLC

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Product Name Qty
5-Azacytidine
250 mg
$150.77
5-Azacytidine
50 mg
$50.26

A potent growth inhibitor and cytotoxic agent; a potent DNA methyltransferase inhibitor.Causes DNA demethylation or hemi-demethylation, creating openings that allow transcription factors to bind to DNA and reactivate tumor suppressor genes. Also recently shown to increase the reprogramming efficiency of stem cells to 10-fold.

More Information
Alternate Name/Synonyms
Ladakamycin, Vidaza, Azadine
SKU
A-2172
CAS #
320-67-2
Chemical Name
4-Amino-1-(β-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one
Chemical Formula
C8H12N4O5
Molecular Weight
244.3 g/mol
Appearance
White to off-white Solid
Purity
98% by TLC
Solubility
Soluble in AcOH (5 mg/ml)
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
5-Azacytidine is a potent growth inhibitor and a cytotoxic agent
MDL NUMBER
MFCD00006539
CHEMACX
X1005308-2
INCHI
InChI=1S/C8H12N4O5/c9-7-10-2-12(8(16)11-7)6-5(15)4(14)3(1-13)17-6/h2-6,13-15H,1H2,(H2,9,11,16)/t3-,4-,5-,6-/m1/s1
SMILES
c1nc(nc(=O)n1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)N
Peptide sequence
Not Applicable
RTECS
XZ3017500
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from air and light
Certificate of Analysis 1
/media/upload/pdf/A-2172, E1361.pdf
Certificate of Analysis 2
/media/upload/pdf/A-2172_A-2172,_C1244.pdf
Promo text for AGS discount
N/A
GHS PICTOGRAMS
Handling Protect from air and light
UN #'S Not Applicable
Packing Group Not Applicable
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