7-Amino-Actinomycin D Streptomyces sp.

SKU
A-1132
  • CAS:7240-37-1
  • Formula:C62 H87 N13 O16
  • MW:1270.43
  • Appearance:Purple Powder
  • Purity:98%

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Product Name Qty
7-Amino-Actinomycin D Streptomyces sp.
1 mg
$107.20
7-Amino-Actinomycin D Streptomyces sp.
5 mg
$368.75

7-Amino-Actinomycin D is a most popular cell-impermeant Fluorescent DNA Stain. Binds Single stranded DNA. Useful tool in determining apoptosis. Also available, Actinomycin D #A-1022.

 

 

More Information
Alternate Name/Synonyms
7-AAD
SKU
A-1132
CAS #
7240-37-1
Chemical Name
2,7-DIAMINO-4,6-DIMETHYL-3-OXO-1-N,9-N-BIS[(3R,6S,7R,10S,16S)-7,11,14-TRIMETHYL-2,5,9,12,15-PENTAOXO-3,10-DI(PROPAN-2-YL)-8-OXA-1,4,11,14-TETRAZABICYCLO[14.3.0]NONADECAN-6-YL]PHENOXAZINE-1,9-DICARBOXAMIDE
Chemical Formula
C62 H87 N13 O16
Molecular Weight
1270.43
Appearance
Purple Powder
Purity
98%
Solubility
Soluble in Water
Melting Point
258 - 260°C
Storage Temp
+4°C
THERAPEUTIC AREA
Not Available
USE
7-Aminoactinomycin D (7-AAD), an analog of the antibiotic actinomycin D, is a fluorescent DNA dye.
MDL NUMBER
MFCD00077295
CHEMACX
X1086975-1
INCHI
InChI=1S/C62H87N13O16/c1-26(2)42-59(85)74-21-17-19-36(74)57(83)70(13)24-38(76)72(15)48(28(5)6)61(87)89-32(11)44(55(81)66-42)68-53(79)34-23-35(63)30(9)51-46(34)65-47-40(41(64)50(78)31(10)52(47)91-51)54(80)69-45-33(12)90-62(88)49(29(7)8)73(16)39(77)25-71(14)58(84)37-20-18-22-75(37)60(86)43(27(3)4)67-56(45)82/h23,26-29,32-33,36-37,42-45,48-49H,17-22,24-25,63-64H2,1-16H3,(H,66,81)(H,67,82)(H,68,79)(H,69,80)/t32-,33-,36+,37+,42-,43-,44+,45+,48+,49?/m1/s1
SMILES
Cc1c(cc(c2c1oc-3c(c(=O)c(c(c3n2)C(=O)N[C@H]4[C@H](OC(=O)C(N(C(=O)CN(C(=O)[C@@H]5CCCN5C(=O)[C@H](NC4=O)C(C)C)C)C)C(C)C)C)N)C)C(=O)N[C@H]6[C@H](OC(=O)[C@@H](N(C(=O)CN(C(=O)[C@@H]7CCCN7C(=O)[C@H](NC6=O)C(C)C)C)C)C(C)C)C)N
Peptide sequence
Not Applicable
RTECS
AU1579000
UN #'S
UN 3462
PACKING GROUP
II
HAZARD CLASS
Not Applicable
Handling
Warning.Toxic. Wear gloves/mask when handling product. Avoid contact by all means of exposure. Protect from Light Hygroscopic.
Citations
VIRUS-CELL INTERACTIONS: DNA Damage Response Signaling Triggers Nuclear Localization of the Chicken Anemia Virus Protein Apoptin Thomas J. Kucharski, Isabelle Gamache, Ole Gjoerup, and Jose G. Teodoro J. Virol., Dec 2011; 85: 12638 - 12649.
Citations_Hyperlink
http://jvi.asm.org/cgi/reprint/85/23/12638
Certificate of Analysis 1
Certificate of Analysis 2
Certificate of Analysis 3
GHS PICTOGRAMS
Handling Warning.Toxic. Wear gloves/mask when handling product. Avoid contact by all means of exposure. Protect from Light Hygroscopic.
UN #'S UN 3462
Packing Group II
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