7-Oxostaurosporine

SKU
O-2563
  • CAS:141196-69-2
  • Formula:C28H24N4O4
  • MW:480.5
  • Appearance:Yellow solid
  • Purity:>98% by HPLC
Product Name Qty
7-Oxostaurosporine
5 mg
$1,243.86
7-Oxostaurosporine
1 mg
$355.39
*Please inquire the availability for this product. 7-Oxostaurosporine is the oxidised and highly fluorescent analogue of UCN-01 and UCN-02. 7-Oxostaurosporine is a potent inhibitor of protein kinase C and formation of cellular blebs induced by phorbols. It inhibits the cell cycle at the G2 stage with the accumulation of 4C DNA cells and possesses comparable activity against tumor cells lines to UCN-01. Despite its close relationship to UCN-01 and staurosporine, limited access to the metabolite has restricted a more complete investigation of its properties.
More Information
Alternate Name/Synonyms
7-Oxostaurosporine, BMY 41950, RK 1409
SKU
O-2563
CAS #
141196-69-2
Chemical Formula
C28H24N4O4
Molecular Weight
480.5
Appearance
Yellow solid
Purity
>98% by HPLC
Solubility
Soluble in DMSO, DMF, ethanol, methanol, and water (limited)
Melting Point
346.61 °C
Storage Temp
-20°C
MDL NUMBER
MFCD14635428
INCHI
InChI=1S/C28H24N4O4/c1-28-25(35-3)15(29-2)12-18(36-28)31-16-10-6-4-8-13(16)19-21-22(27(34)30-26(21)33)20-14-9-5-7-11-17(14)32(28)24(20)23(19)31/h4-11,15,18,25,29H,12H2,1-3H3,(H,30,33,34)/t15-,18-,25-,28+/m1/s1
SMILES
O=C5c4c2c3n(c1ccccc12)[C@]8(O[C@@H](n6c3c(c4C(=O)N5)c7ccccc67)C[C@@H](NC)[C@H]8OC)C
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