8-Br-cAMP

SKU
B-2173
  • CAS:76939-46-3
  • Formula:C10H10BrN5O6P. Na
  • MW:430.08
  • Appearance:White to off-white Solid
  • Purity:98% by TLC

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Product Name Qty
8-Br-cAMP
25 mg
$184.26
8-Br-cAMP
5 mg
$61.42

A cell-permeable cAMP analog that is more resistant to hydrolysis by phosphodiesterases than cAMP. Activates protein kinase A, inhibits growth, decreases proliferation, increases differentiation, and induces apoptosis of cultured cells. Also recently shown to improve the reprogramming efficiency of human neonatal foreskin fibroblast (HFF1) cells 2-fold.

More Information
Alternate Name/Synonyms
8- Bromoadenosine- 3', 5'- cyclic monophosphate; cyclic 8- bromoadenosine- 3', 5'- monophosphate; 8- bromoadenosine- 3', 5'-Monophosphate
SKU
B-2173
CAS #
76939-46-3
Chemical Name
8- Bromoadenosine- 3', 5'- cyclic monophosphate; cyclic 8- bromoadenosine- 3', 5'- monophosphate; 8- bromoadenosine- 3', 5'-Monophosphate
Chemical Formula
C10H10BrN5O6P. Na
Molecular Weight
430.08
Appearance
White to off-white Solid
Purity
98% by TLC
Solubility
Soluble in H2O (~100 mg/ml)
Stability
N/A
Melting Point
233.9-235 °C
Storage Temp
-20°C
THERAPEUTIC AREA
Not Available
USE
A cell-permeable cAMP analog that is more resistant to hydrolysis by phosphodiesterases than cAMP
MDL NUMBER
MFCD00005844
CHEMACX
X1087628-1
INCHI
InChI=1S/C10H11BrN5O6P.Na/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-5(17)6-3(21-9)1-20-23(18,19)22-6;/h2-3,5-6,9,17H,1H2,(H,18,19)(H2,12,13,14);/q;+1/p-1/t3-,5-,6-,9-;/m1./s1
SMILES
c1nc(c2c(n1)n(c(n2)Br)[C@H]3[C@@H]([C@H]4[C@H](O3)COP(=O)(O4)[O-])O)N.[Na+]
Peptide sequence
Not Applicable
RTECS
AU7357292
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from moisture and light
Promo text for AGS discount
N/A
Handling Protect from moisture and light
UN #'S Not Applicable
Packing Group Not Applicable
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