8-Br-cGMP

SKU
B-2174
  • CAS:51116-01-9
  • Formula:C10H10BrN5O7P. Na
  • MW:446.08
  • Appearance:White to off-white Solid
  • Purity:95% by TLC

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Product Name Qty
8-Br-cGMP
25 mg
$217.76
8-Br-cGMP
5 mg
$72.59

A cell-permeable cGMP analog having greater resistance to hydrolysis by phosphodiesterases than cGMP. Activates cGMP-dependent protein kinase (PKG), slows or inhibits the intracellular calcium oscillations of tracheal smooth muscle cells in response to acetylcholine. It inhibits thrombin stimulated arachidonic acid release in human platelets.

More Information
Alternate Name/Synonyms
8- Bromoguanosine- 3', 5'- cyclic monophosphate, cyclic 8- bromoguanosine- 3', 5'- monophosphate, 8- bromoguanosine- 3', 5'-monophosphate
SKU
B-2174
CAS #
51116-01-9
Chemical Name
8- Bromoguanosine- 3', 5'- cyclic monophosphate, cyclic 8- bromoguanosine- 3', 5'- monophosphate, 8- bromoguanosine- 3', 5'-monophosphate
Chemical Formula
C10H10BrN5O7P. Na
Molecular Weight
446.08
Appearance
White to off-white Solid
Purity
95% by TLC
Solubility
Soluble in H2O (~25 mg/ml) or aqueous buffers
Storage Temp
-20°C
THERAPEUTIC AREA
Not Available
USE
A cell-permeable cGMP analog resistance to hydrolysis than cGMP
MDL NUMBER
MFCD00070128
CHEMACX
Not Applicable
INCHI
InChI=1S/C10H11BrN5O7P.Na/c11-9-13-3-6(14-10(12)15-7(3)18)16(9)8-4(17)5-2(22-8)1-21-24(19,20)23-5;/h2,4-5,8,17H,1H2,(H,19,20)(H3,12,14,15,18);/q;+1/p-1/t2-,4-,5-,8-;/m1./s1
SMILES
C1[C@@H]2[C@H]([C@H]([C@@H](O2)n3c4c(c(=O)[nH]c(n4)N)nc3Br)O)OP(=O)(O1)[O-].[Na+]
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from moisture and light
Certificate of Analysis 1
Promo text for AGS discount
N/A
Handling Protect from moisture and light
UN #'S Not Applicable
Packing Group Not Applicable
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