A-54556B

SKU
A-2577
  • CAS:95398-44-0
  • Formula:C37H48N6O8
  • MW:704.8
  • Appearance:Beige powder
Product Name Qty
A-54556B
0.5 mg
$335.02
A-54556B
2.5 mg
$1,172.57
A 54556B is an unusual depsipeptide isolated from Streptomyces hawaiiensis as antibiotics by researchers at Eli Lilly in 1985, featuring a trienone side chain. A 54556B is a potent antibacterial against Gram positive and Gram negative bacteria including MRSA. A 54556B is a member of the recently re-discovered acyldepsipeptide (ADEP) antibiotics that act by activating and disregulating Clp-family proteins. ADEPs are considered important leads in the development of new generations of antibiotics against resistant bacteria.
More Information
SKU
A-2577
CAS #
95398-44-0
Chemical Name
N-ALPHA-[(2E,4E,6E)-2,4,6-OCTATRIENOYL]-N-[(6S,9S,11AS,17S,20AS)-6,9,10-TRIMETHYL-5,8,11,16,20-PENTAOXOHEXADECAHYDRO-1H,5H,16H-DIPYRROLO[2,1-C:2',1'-L][1,4,7,10,13]OXATETRAAZACYCLOHEXADECIN-17-YL]-L-PH ENYLALANINAMIDE
Chemical Formula
C37H48N6O8
Molecular Weight
704.8
Appearance
Beige powder
Solubility
>95% by HPLC
Stability
N/A
Storage Temp
-20° C
THERAPEUTIC AREA
Infectious Diseases
USE
A potent antibacterial agent against Gram positive and Gram negative bacteria
INCHI
InChI=1S/C37H48N6O8/c1-5-6-7-8-12-19-31(44)39-27(22-26-15-10-9-11-16-26)33(46)40-28-23-51-37(50)30-18-14-21-43(30)34(47)24(2)38-32(45)25(3)41(4)36(49)29-17-13-20-42(29)35(28)48/h5-12,15-16,19,24-25,27-30H,13-14,17-18,20-23H2,1-4H3,(H,38,45)(H,39,44)(H,40,46)/b6-5+,8-7+,19-12+/t24-,25-,27-,28-,29-,30-/m0/s1
SMILES
C/C=C/C=C/C=C/C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H]2COC(=O)[C@@H]3CCCN3C(=O)[C@@H](NC(=O)[C@@H](N(C(=O)[C@@H]4CCCN4C2=O)C)C)C
Cat. #
MST-A1571
Promo text for AGS discount
N/A
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