A23187, Mixed Calcium-Magnesium Salt
- Appearance:White powder
A23187 has antifungal properties, its antibacterial activities are targeted towards gram positive bacteria.
The divalent cation ionophore activity of A23187 is utilized in laborotories to to increase intracellular Ca2+ levels in intact cells.A23187 also induces apoptosis in some cells (e.g. mouse lymphoma cell line, or S49, and Jurkat cells) and prevents it in others (e.g. cells dependent on interlukin 3 that have had the factor withdrawn).
Used in cell activation experiments when calcium dose-response data are not required. Molar ratio Ca:Mg (1:1).
Not for human therapeutic use or for medicinal purposes. For research applications only.
|Handling||Avoid contact with skin, eyes or clothing. Use personal protective equipment as required. Wash contaminated clothing before reuse. Do not breathe dust/fume/gas/mist/vapors/spray. Do not eat, drink or smoke when using this product|
|UN #'S||UN 3462|