A23187, Mixed Calcium-Magnesium Salt

SKU
A-1128
  • Appearance:White powder
  • Purity:≥98%

0

1

0

Product Name Qty
A23187, Mixed Calcium-Magnesium Salt
10 mg
$137.70
A23187, Mixed Calcium-Magnesium Salt
5 mg
$81.60

Description

A23187 has antifungal properties, its antibacterial activities are targeted towards gram positive bacteria.

The divalent cation ionophore activity of A23187 is utilized in laborotories to to increase intracellular Ca2+ levels in intact cells.A23187 also induces apoptosis in some cells (e.g. mouse lymphoma cell line, or S49, and Jurkat cells) and prevents it in others (e.g. cells dependent on interlukin 3 that have had the factor withdrawn).

Used in cell activation experiments when calcium dose-response data are not required. Molar ratio Ca:Mg (1:1).

 


Not for human therapeutic use or for medicinal purposes. For research applications only.

More Information
Alternate Name/Synonyms
A23187 Ca Mg
SKU
A-1128
Appearance
White powder
Purity
≥98%
Solubility
Clear colorless solution at 10 mg/mL Dichloromethane
Melting Point
309 °C
Storage Temp
-20°C
THERAPEUTIC AREA
Antifungal, antibacterial
USE
A compound used in cell activation. Calcium ionophore.
MDL NUMBER
MFCD00213962
CHEMACX
X6952231-2
INCHI
InChI=1S/4C28H34N2O6.Ca.Mg/c4*1-15-10-11-28(17(3)13-16(2)26(36-28)18(4)25(31)20-8-6-12-29-20)35-22(15)14-23-30-24-19(27(32)33)7-5-9-21(24)34-23;;/h4*5-9,12,15-18,22,26,29H,10-11,13-14H2,1-4H3,(H,32,33);;/q;;;;2*+2/p-4/t4*15-,16-,17-,18-,22-,26+,28-;;/m1111../s1
SMILES
C[C@@H]1CC[C@@]2([C@@H](C[C@H]([C@H](O2)[C@H](C)C(=O)c3ccc[nH]3)C)C)O[C@@H]1Cc4nc5c(cccc5o4)C(=O)O[Mg]OC(=O)c6cccc7c6nc(o7)C[C@@H]8[C@@H](CC[C@]9(O8)[C@@H](C[C@H]([C@H](O9)[C@H](C)C(=O)c1ccc[nH]1)C)C)C.C[C@@H]1CC[C@@]2([C@@H](C[C@H]([C@H](O2)[C@H](C)C(=O)
UN #'S
UN 3462
PACKING GROUP
III
Handling
Avoid contact with skin, eyes or clothing. Use personal protective equipment as required. Wash contaminated clothing before reuse. Do not breathe dust/fume/gas/mist/vapors/spray. Do not eat, drink or smoke when using this product
Certificate of Analysis 1
GHS PICTOGRAMS
Handling Avoid contact with skin, eyes or clothing. Use personal protective equipment as required. Wash contaminated clothing before reuse. Do not breathe dust/fume/gas/mist/vapors/spray. Do not eat, drink or smoke when using this product
UN #'S UN 3462
Packing Group III
To Top