A23187, Mixed Calcium-Magnesium Salt
- Formula:C56 H66 Ca N4 O12 . C56 H66 Mg N4 O12
- Appearance:White Powder
- Purity:>98% (etOAC : Petroleum ether 8:2)
A23187 has antifungal properties, its antibacterial activities are targeted towards gram positive bacteria. The divalent cation ionophore activity of A23187 is utilized in laborotories to to increase intracellular Ca2+ levels in intact cells.A23187 also induces apoptosis in some cells (e.g. mouse lymphoma cell line, or S49, and Jurkat cells) and prevents it in others (e.g. cells dependent on interlukin 3 that have had the factor withdrawn). Used in cell activation experiments when calcium dose-response data are not required. Molar ratio Ca:Mg (1:1).
|Handling||Warning.Toxic. Wear gloves/mask when handling product. Avoid contact by all means of exposure. Protect from Light|
|UN #'S||UN 3462|