A23187, Mixed Calcium-Magnesium Salt

SKU
A-1128
  • Formula:C56 H66 Ca N4 O12 . C56 H66 Mg N4 O12
  • MW:2038.69
  • Appearance:White Powder
  • Purity:>98% (etOAC : Petroleum ether 8:2)

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Product Name Qty
A23187, Mixed Calcium-Magnesium Salt
10 mg
$134.79
A23187, Mixed Calcium-Magnesium Salt
5 mg
$60.52

A23187 has antifungal properties, its antibacterial activities are targeted towards gram positive bacteria. The divalent cation ionophore activity of A23187 is utilized in laborotories to to increase intracellular Ca2+ levels in intact cells.A23187 also induces apoptosis in some cells (e.g. mouse lymphoma cell line, or S49, and Jurkat cells) and prevents it in others (e.g. cells dependent on interlukin 3 that have had the factor withdrawn). Used in cell activation experiments when calcium dose-response data are not required. Molar ratio Ca:Mg (1:1).

 

More Information
SKU
A-1128
Chemical Name
BIS[[2-[[(3R,4R,6R,7R,9R,10S)-3,7,9-TRIMETHYL-10-[(1S)-1-METHYL-2-OXO-2-(1H-PYRROL-2-YL)ETHYL]-5,11-DIOXASPIRO[5.5]UNDECAN-4-YL]METHYL]-1,3-BENZOXAZOLE-4-CARBONYL]OXY]CALCIUM; BIS[[2-[[(3R,4R,6R,7R,9R,10S)-3,7,9-TRIMETHYL-10-[(1S)-1-METHYL-2-OXO-2-(1H-PYR
Chemical Formula
C56 H66 Ca N4 O12 . C56 H66 Mg N4 O12
Molecular Weight
2038.69
Appearance
White Powder
Purity
>98% (etOAC : Petroleum ether 8:2)
Solubility
Soluble in DMSO, Chloroform, and Ethylacetate.
Melting Point
309 °C
Storage Temp
+4°C
THERAPEUTIC AREA
Not Available
USE
A compound used in cell activation
MDL NUMBER
MFCD00213962
CHEMACX
X6952231-2
INCHI
InChI=1S/4C28H34N2O6.Ca.Mg/c4*1-15-10-11-28(17(3)13-16(2)26(36-28)18(4)25(31)20-8-6-12-29-20)35-22(15)14-23-30-24-19(27(32)33)7-5-9-21(24)34-23;;/h4*5-9,12,15-18,22,26,29H,10-11,13-14H2,1-4H3,(H,32,33);;/q;;;;2*+2/p-4/t4*15-,16-,17-,18-,22-,26+,28-;;/m1111../s1
SMILES
C[C@@H]1CC[C@@]2([C@@H](C[C@H]([C@H](O2)[C@H](C)C(=O)c3ccc[nH]3)C)C)O[C@@H]1Cc4nc5c(cccc5o4)C(=O)O[Mg]OC(=O)c6cccc7c6nc(o7)C[C@@H]8[C@@H](CC[C@]9(O8)[C@@H](C[C@H]([C@H](O9)[C@H](C)C(=O)c1ccc[nH]1)C)C)C.C[C@@H]1CC[C@@]2([C@@H](C[C@H]([C@H](O2)[C@H](C)C(=O)
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
UN 3462
PACKING GROUP
III
HAZARD CLASS
Not Applicable
Handling
Warning.Toxic. Wear gloves/mask when handling product. Avoid contact by all means of exposure. Protect from Light
Certificate of Analysis 1
/media/upload/pdf/A-1128_A-1128,_A7534.pdf
GHS PICTOGRAMS
Handling Warning.Toxic. Wear gloves/mask when handling product. Avoid contact by all means of exposure. Protect from Light
UN #'S UN 3462
Packing Group III
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