A77 1726
SKU
A-2176
- CAS:108605-62-5
- Formula:C12H9F3N2O2
- MW:270.21
- Appearance:White solid
- Purity:≥98% by HPLC
SDS
CofA
A77 1726 physiologically active metabolite of the immunosuppressive drug leflunomide (Cat. No.1972-10, 50). A77 1726 Inhibits the activity of dihydroorotate dehydrogenase and of protein tyrosine kinases. A77 1726 Blocks TNF-mediated NF-κB activation in a dose- and time-dependent manner. A77 1726 Also inhibits the activity of COX-2 in vitro and in vivo.
More Information
Alternate Name/Synonyms
Teriflunomide
SKU
A-2176
CAS #
108605-62-5
Chemical Name
(Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide
Chemical Formula
C12H9F3N2O2
Molecular Weight
270.21
Appearance
White solid
Purity
≥98% by HPLC
Solubility
DMSO
Storage Temp
-20°C
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