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AG 1112

SKU
A-1176
  • Formula:C15H10N6
  • MW:274.28
  • Appearance:Off-White to Yellow Solid
  • Purity:98%
Product Name Qty
AG 1112
1 mg
$60.13
AG 1112
5 mg
$126.31
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AG 1112 also known as Tyrphostin AG 1112 is a Casein Kinase II inhibitor. It is a Bcr-Abl Kinase blocker that stimulates and activates the terminal differentiation of K562 cells and the purging of Ph+ cells. AG 1112 has been suggested to be regulatory in function, some of them are cell proliferation, cell differentiation, and apoptosis.

 

 

 

 

 

 

More Information
Alternate Name/Synonyms
Tyrphostin AG 1112
SKU
A-1176
Chemical Name
(5Z)-3-AMINO-5-[(2Z)-1-CYANO-2-INDOL-3-YLIDENEETHYLIDENE]-1,2-DIHYDROPYRAZOLE-4-CARBONITRILE
Chemical Formula
C15H10N6
Molecular Weight
274.28
Appearance
Off-White to Yellow Solid
Purity
98%
Solubility
Soluble in DMSO (5mg/ml), acetone or ethyl acetate; insoluble in dichloromethane.
Storage Temp
-20°C
MDL NUMBER
MFCD01868804
INCHI
InChI=1S/C15H10N6/c16-6-9(14-12(7-17)15(18)21-20-14)5-10-8-19-13-4-2-1-3-11(10)13/h1-5,8,20-21H,18H2/b10-5+,14-9-
SMILES
C1=CC=C2C(=C1)/C(=C/C(=C/3C(=C(NN3)N)C#N)/C#N)/C=N2
Handling
Store in Tightly Sealed Vial Protect from Light
GHS PICTOGRAMS
HandlingStore in Tightly Sealed Vial Protect from Light
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