SDS
CofA
Tyrosine kinase inhibitor reported to block TNFα induced cytotoxicity. Also blocks glucocorticoid-induced COX-2 activity in human amnion cells (IC50=21μM). It has the ability to block LPS-induced production of nitric oxide in macrophages and tumor necrosis factor alpha.
More Information
Alternate Name/Synonyms
alpha-Cyano-(3,4-dihydroxy-5-nitro)cinnamonitrile
SKU
A-1192
CAS #
116313-73-6
Chemical Name
2-[(3,4-Dihydroxy-5-nitrophenyl)methylidene]propanedinitrile
Chemical Formula
C10H5N3O4
Molecular Weight
231.2
Appearance
Orange Solid
Purity
≥98%
Solubility
Soluble in Water, Methanol or DMSO
Storage Temp
Room Temp, -20°C
