AG 879
SKU
A-1198
- CAS:148741-30-4
- Formula:C18H24N2OS
- MW:316.5
- Appearance:Off-white to yellow solid
- Purity:≥98%

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AG 879 or Tyrphostin AG 879 inhibits the tyrosine kinase activity of nerve growth factor(NGF)-dependent TrKA tyrosine phosphorylation in in PC-12 cells (IC50 = ~40 μM), HER2-ErbB2 kinase in several breast and ovarian cancer cell lines (IC50 = ~0.5 μM). It acts as an antiproliferative agent for diseases caused by the hyperactivity of PTKs. AG-
More Information
Alternate Name/Synonyms
Tyrphostin AG 879
SKU
A-1198
CAS #
148741-30-4
Chemical Name
(3,5-Di-t-butyl-4-hydroxybenzylidene)thiocyanoacetamide alpha-Cyano-(3,5-di-tert.butyl-4-hydroxy)thiocinnamamide
Chemical Formula
C18H24N2OS
Molecular Weight
316.5
Appearance
Off-white to yellow solid
Purity
≥98%
Solubility
Soluble in DMSO and Ethanol.
Storage Temp
-20°C