AICAr

SKU
A-1716
  • CAS:2627-69-2
  • Formula:C9H14N4O5
  • MW:258.23 Da
  • Appearance:Tan powder
  • Purity:≥98% (HPLC)

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Product Name Qty
AICAR
250 mg
$220.00
AICAR
50 mg
$65.00

To order chemical components, please provide appropriate identification including business license and address. This product is for research/laboratory use only - not sold for human consumption.

Description

AICAr (AICA-Riboside) is a cell- permeable activator of AMP-activated protein kinase (AMPK), a metabolic sensor involved in both cellular and whole body energy homeostasis. In vivo, pharmacologic activation of AMPK with AICAR mimics exercise and triggers insulin-independent glucose uptake by skeletal muscle. AICAR is able to activate the molecular circuitry of pluripotency in mESC and to induce the expression of several key regulators of pluripotency in somatic cells.

 

Applications and Effects of AICAr

• AICAr's phosphorylated metabolite activates AMPK and acts as a regulator of de novo purine synthesis.
• Kinase phosphatase biology research.
• For laboratory and research use only. Not for human consumption.

 

 

More Information
Alternate Name/Synonyms
AICA-Riboside, NSC 105823, Acadesine, Acadesine, AICAr, 5-Aminoimidazole-4-carboxamide-1-β-riboside, Z-Riboside, AMPK Signaling Activator II
SKU
A-1716
CAS #
2627-69-2
Chemical Name
5-Aminoimidazole-4-carboxamide 1-β-D-ribofuranoside
Chemical Formula
C9H14N4O5
Molecular Weight
258.23 Da
Appearance
Tan powder
Purity
≥98% (HPLC)
Solubility
Water
Storage Temp
-20°C
USE
Kinase phosphatase research.
Handling
Research use only.
Certificate of Analysis 1
GHS PICTOGRAMS
Handling Research use only.
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