- Appearance:White to off-white Powder
Potent and selective inhibitor of AKT or Protein Kinase B. AKT inhibitors evolved from adenosine triphosphate (ATP). AKT inhibitors have a potential clinical application in anti-cancer drug development . Weak inhibitor of phosphatidylinositol 3-kinase (PI3-K) (IC= 83 M). Has been shown to inhibit the growth of the following cancer cell lines: HeLa (IC= 2.5 M), HT-29 (IC= 10 M), MCF-7 (IC= 1.2 M), and PC-3 (IC= 2.0 M).
|Handling||Hygroscopic. Protect from air and moisture. Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 weeks at -20°C.|