AKT INHIBITOR

SKU
A-1762
  • Formula:C30H58O10
  • MW:578.8
  • Appearance:White to off-white Powder
  • Purity:98%

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Product Name Qty
AKT INHIBITOR
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$0.00

Potent and selective inhibitor of AKT or Protein Kinase B. AKT inhibitors evolved from adenosine triphosphate (ATP). AKT inhibitors have a potential clinical application in anti-cancer  drug development . Weak inhibitor of phosphatidylinositol 3-kinase (PI3-K) (IC= 83 M). Has been shown to inhibit the growth of the following cancer cell lines: HeLa (IC= 2.5 M), HT-29 (IC= 10 M), MCF-7 (IC= 1.2 M), and PC-3 (IC= 2.0 M).

More Information
SKU
A-1762
Chemical Name
1l-6-hydroxymethyl-chiro-inositol-2-r-2-o-methyl-3-o-octadecylcarbonate
Chemical Formula
C30H58O10
Molecular Weight
578.8
Appearance
White to off-white Powder
Purity
98%
Solubility
Soluble in DMSO (200 mg/ml). Use anhydrous DMSO for reconstitution.
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
Potent inhibitor of Akt use in cancer
MDL NUMBER
MFCD03454086
INCHI
InChI=1S/C30H58O10/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-38-21-23(37-2)22-39-30(36)40-29-26(33)24(20-31)25(32)27(34)28(29)35/h23-29,31-35H,3-22H2,1-2H3/t23-,24+,25-,26-,27+,28-,29-/m1/s1
SMILES
CCCCCCCCCCCCCCCCCCOC[C@H](COC(=O)O[C@@H]1[C@@H]([C@H]([C@H]([C@@H]([C@H]1O)O)O)CO)O)OC
Handling
Hygroscopic. Protect from air and moisture. Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 weeks at -20°C.
Handling Hygroscopic. Protect from air and moisture. Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 weeks at -20°C.
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