Alamethicin F50

SKU
A-2591
  • CAS:56165-93-6
  • Formula:C92H151N23O24
  • MW:1963.4 Da
  • Appearance:Off-white solid
  • Purity:>98% by HPLC
Product Name Qty
Alamethicin F50
2.5 mg
$145.17
Alamethicin F50
10 mg
$507.00

Description

Alamethicin F50 is a neutral linear peptaibol complex with potent antibiotic activity, containing 20 “amino acids” with acetyl and phenylalaninol termini, produced by Trichoderma sp.. Alamethicin F50 acts an ionopohore, transporting ions through membranes and artificial lipid membranes. Alamethicin F50 forms voltage-dependent ion channels in lipid bilayer membranes.

Alamethicin F50 is co-produced with an acidic linear peptaibol complex (alamethicin F30). Alamethicin itself is a variable mixture of the acidic and neutral components. In general, reports on alamethicin do not specify the ratio of F50 to F30 in the complex and comparative data between the complexes is scant.

Isolated from Trichoderma viride.

Not for human therapeutic use or for medicinal purposes. For research applications only.

More Information
Alternate Name/Synonyms
Alamethicin F; Alamethicin Rf 50; Atroviridin A; 18-L-Glutamine-alamethicin I
SKU
A-2591
CAS #
56165-93-6
Chemical Name
18-L-GLUTAMINE-ALAMETHICIN I
Chemical Formula
C92H151N23O24
Molecular Weight
1963.4 Da
Appearance
Off-white solid
Purity
>98% by HPLC
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
Storage Temp
-20°C
THERAPEUTIC AREA
Antibiotic
USE
A potent antibiotic which forms voltage-dependent ion channels in lipid bilayers (ionophore)
Cat. #
MST-A1543
Certificate of Analysis 1
Certificate of Analysis 2
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