AM-80

SKU
A-2531
  • CAS:94497-51-5
  • Formula:C22 H25 N O3
  • MW:351.444
  • Appearance:Solid
Product Name Qty
AM-80
10 mg
$169.73
AM-80
50 mg
$682.31
RARα agonist
More Information
SKU
A-2531
CAS #
94497-51-5
Chemical Name
4-[(5,5,8,8-TETRAMETHYL-6,7-DIHYDRONAPHTHALEN-2-YL)CARBAMOYL]BENZOIC ACID
Chemical Formula
C22 H25 N O3
Molecular Weight
351.444
Appearance
Solid
Solubility
Soluble in 1.1eq. NaOH (100 mM), DMSO (50 mM), methanol, and water 
Storage Temp
Room Temp
THERAPEUTIC AREA
Oncological Disorders
USE
AM 80 is a retinoic acid receptor α (RARα) agonist that induces differentiation and apoptosis of HL-60 cells displays anticancer activity against acute promyelocytic leukemia
MDL NUMBER
MFCD00866188
CHEMACX
X1276933-4
INCHI
InChI=1S/C22H25NO3/c1-21(2)11-12-22(3,4)18-13-16(9-10-17(18)21)23-19(24)14-5-7-15(8-6-14)20(25)26/h5-10,13H,11-12H2,1-4H3,(H,23,24)(H,25,26)
SMILES
CC1(CCC(c2c1ccc(c2)NC(=O)c3ccc(cc3)C(=O)O)(C)C)C
RTECS
DH6940000
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