Amidepsine D

SKU
A-1450
  • Formula:C26H24O10
  • MW:496.5
  • Appearance:White to light pink Powder
  • Purity:95% (HPLC)
Product Name Qty
Amidepsine D
250 ug
$118.46
Amidepsine D
1 mg
$364.51
Amidepsine D
2.5 mg
$523.97
Inhibitor of diacylglycerol acyltransferase (DGAT). Shows inhibitory effect in rat liver microsomes (IC=17.5 M) and Raji cells (IC=2.8 M). Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia, which may lead to atherosclerosis, diabetes and metabolic disorders.
More Information
SKU
A-1450
Chemical Name
4-[(2,4-DIMETHOXY-6-METHYLBENZOYL)OXY]-2-HYDROXY-6-METHYL-BENZOIC ACID 4-CARBOXY-3-HYDROXY-5-METHYLPHENYL ESTER
Chemical Formula
C26H24O10
Molecular Weight
496.5
Appearance
White to light pink Powder
Purity
95% (HPLC)
Solubility
Soluble in methanol (1mg/ml); insoluble in water
Storage Temp
-20°C
THERAPEUTIC AREA
Vascular Disorders
USE
Amidepsine A is an inhibitor of DGAT (diacylglycerol acyltransferase) use in atherosclerosis, diabetes and metabolic disorders
MDL NUMBER
MFCD28138426
CHEMACX
Not Applicable
INCHI
InChI=1S/C26H24O10/c1-12-7-16(9-18(27)21(12)24(29)30)35-25(31)22-13(2)8-17(10-19(22)28)36-26(32)23-14(3)6-15(33-4)11-20(23)34-5/h6-11,27-28H,1-5H3,(H,29,30)
SMILES
CC1=CC(=CC(=C1C(=O)O)O)OC(=O)C2=C(C=C(C=C2C)OC(=O)C3=C(C=C(C=C3C)OC)OC)O
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
GHS PICTOGRAMS
UN #'S Not Applicable
Packing Group Not Applicable
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