Anguinomycin A

SKU
A-2599
  • CAS:111278-01-4
  • Formula:C31H44O6
  • MW:512.7
  • Appearance:Pale yellow film
  • Purity:>95% by HPLC
Product Name Qty
Anguinomycin A
0.5 mg
$1,641.60
Anguinomycin A
0.1 mg
$469.03
*Please inquire the availability for this product. Anguinomycin A, isolated from a Streptomyces sp., displays nanomolar cytotoxicity to murine P388 leukemia cells. In addition, it shows antitumor activity in vivo against murine Lewis lung carcinoma and P388 leukemia. Anguinomycin A is an analogue of leptomycin B, an inhibitor of nuclear export of proteins.
More Information
Alternate Name/Synonyms
5-Demethylleptomycin A, KR 2827A
SKU
A-2599
CAS #
111278-01-4
Chemical Name
(2E,10E,12E,16Z,18E)-6-HYDROXY-3,5,7,9,11,15,17-HEPTAMETHYL-8-OXO-19-(6-OXO-3,6-DIHYDRO-2H-PYRAN-2-YL)-2,10,12,16,18-NONADECAPENTAENOIC ACID
Chemical Formula
C31H44O6
Molecular Weight
512.7
Appearance
Pale yellow film
Purity
>95% by HPLC
Solubility
Soluble in methanol, and ethanol Insoluble in DMSO
Stability
N/A
Storage Temp
-20° C
THERAPEUTIC AREA
Oncological Disorders
USE
An inhibitor of nuclear export of proteins it shows antitumor activity
MDL NUMBER
MFCD09752704
INCHI
InChI=1S/C31H44O6/c1-20(16-22(3)14-15-27-12-9-13-29(34)37-27)10-8-11-21(2)17-24(5)30(35)26(7)31(36)25(6)18-23(4)19-28(32)33/h8-9,11,13-17,19-20,24-27,31,36H,10,12,18H2,1-7H3,(H,32,33)/b11-8+,15-14+,21-17+,22-16-,23-19+
SMILES
O=C\1OC(/C=C/C(=C\C(C)C\C=C\C(=C\C(C(=O)C(C)C(O)C(CC(=C\C(=O)O)\C)C)C)C)C)C/C=C/1
Cat. #
MST-A1003
Promo text for AGS discount
N/A
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