Ansamitocin P3

SKU
A-2541
  • CAS:66584-72-3
  • Formula:C32H43ClN2O9
  • MW:635.14 Da
  • Appearance:White to off-white powder
  • Purity:>98% (HPLC)

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Hazardous
Product Name Qty
Ansamitocin P3
1 mg
$368.99

Description

Microtubule depolymerizer a microtubule-depolymerizing agent ansamitocin P3 programs dendritic cells toward enhanced anti-tumor. Ansamitocin P3 is a polyketide antibiotic that is isolated from Actinosynnema pretiosum and also exhibits antitumour activity. It can be used as an antimicrobial agent, a metabolite and an antineoplastic agent.

Applications

• Fungal metabolite with antimitotic, antineoplastic activity
• Ansamitocin P3 binds to tubulin and inhibits vinblastine-induced spiral formation

 

More Information
Alternate Name/Synonyms
Maytansinol ISObutyrate; Antibiotic C15003P3
SKU
A-2541
CAS #
66584-72-3
Chemical Name
[(1S,3R,5S,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10,12,14(26),16,18-pentaen-6-yl] 2-methylpropanoate
Chemical Formula
C32H43ClN2O9
Molecular Weight
635.14 Da
Appearance
White to off-white powder
Purity
>98% (HPLC)
Solubility
Methanol (10 mg/1 mL), Dichloromethane (10 mg/1mL)
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
For research and laboratory purpose only.
MDL NUMBER
MFCD00274586
CHEMACX
X1858974-9
PubChecm ID
137704835
INCHI
OPQNCARIZFLNLF-MOXDUHMPSA-N
SMILES
CC1C2CC(C(C=CC=C(CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)CC(C4(C1O4)C)OC(=O)C(C)C)C)C)OC)(NC(=O)O2)O
GHS Pictograms
9
RTECS
OQ2293000
Handling
Use only in area provided with appropriate exhaust ventilation. Keep away from heat and source of ignition. Empty containers pose a fire risk, evaporate residue under fume hood. Ground all equipment containing material. Do not breathe dust.
Spec
GHS PICTOGRAMS
Handling Use only in area provided with appropriate exhaust ventilation. Keep away from heat and source of ignition. Empty containers pose a fire risk, evaporate residue under fume hood. Ground all equipment containing material. Do not breathe dust.
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