Antiserum to-Bcl-X L/S (Purified)

SKU
B-1225
  • Appearance:Liquid. 100 µg of purified antibody in 1ml of 0.05M sodium phosphate buffer containing 0.1% sodium azide and 0.2% gelatin.
Product Name Qty
Antiserum to-Bcl-X L/S (Purified)
100 ug
$435.52

Source: Rabbit. Immunogen: Synthetic peptide corresponding to aa 201-216 of human Bcl-X. Specificity: Recognizes human, mouse, rat Bcl-XL (strongly) and Bcl-XS (moderately). Application: IHC (FS, PS), WB.

Bcl-2 and Bcl-XL are anti-apoptotic paralogues that inhibit apoptosis elicited by a wide variety of stimuli, and play critical roles in cancer development and resistance to treatment. Many clinical studies have indicated that expression of these anti-apoptotic proteins in tumours is associated with poor prognosis. It has therefore been assumed that in cells the essential difference between Bcl-2 and Bcl-XL involves regulation of expression and that they are otherwise functionally similar.

 

Attached are a few published references from researchers who have used our Antiserum product. We respectfully thank them for their trust in our product. Inquire for a full reference list.

 

 

More Information
SKU
B-1225
Appearance
Liquid. 100 µg of purified antibody in 1ml of 0.05M sodium phosphate buffer containing 0.1% sodium azide and 0.2% gelatin.
Solubility
Soluble in acetone, dichloromethane, diethyl ether or DMSO.
Stability
N/A
Storage Temp
+4°C
Citations
NEUROSCIENCE: Bcl-xL induces Drp1-dependent synapse formation in cultured hippocampal neurons Hongmei Li, Yingbei Chen, Adrienne F. Jones, Richard H. Sanger, Leon P. Collis, Richard Flannery, Ewan C. McNay, Tingxi Yu, Robert Schwarzenbacher, Blaise Bossy, Ella Bossy-Wetzel, Michael V. L. Bennett, Marc Pypaert, John A. Hickman, Peter J. S. Smith, J. Marie Hardwick, and Elizabeth A. Jonas PNAS, Feb 2008; 105: 2169 - 2174.
Citations_Hyperlink
http://www.pnas.org/cgi/reprint/105/6/2169
Certificate of Analysis 1
Promo text for AGS discount
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GHS PICTOGRAMS
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