- MW:338.5 Da
- Appearance:White Powder
- Purity:>99% (TLC)
Aphidicolin is a reversible Inhibitor of eukaryotic nuclear DNA replication. cell cycle at early S-phase.N K-independent Activation of c-Jun during Neuronal Apoptosis Induced by Multiple DNA-damaging Agents. DNA AND CHROMOSOMES: Cohesin Acetylation Promotes Sister Chromatid Cohesion Only in Association with the Replication Machinery. CELL BIOLOGY: RET Modulates Cell Adhesion via its Cleavage by Caspase in Sympathetic Neurons.
Isolated from Nigrospora oryzae
Low dose aphidicolin is an inhibitor of the DNA replicative polymerases α , δ, and ε1. Aphidicolin is a potent and specific inhibitor of B-family DNA polymerases2.
|Handling||Warning.Toxic. Potential Carcinogenic. Do not use this compound if you are not fully trained or are unaware of the hazards involved. Wear gloves/mask when handling product. Avoid contact by all means of exposure. Avoid contact with skin, eyes or clothing. Do not breathe dust/fume/gas/mist/vapors/spray. Do not eat, drink or smoke when using this product. Use with local exhaust ventilation.|
|UN #'S||Not Applicable|
|Packing Group||Not Applicable|