Apicidin

SKU
A-1264
  • CAS:183506-66-3
  • Formula:C34H49N5O6
  • MW:623.8
  • Appearance:White to Off-white
  • Purity:95% (HPLC)

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Product Name Qty
Apicidin
1 mg
$59.96
Apicidin
5 mg
$237.41

A potent oral chemotherapeutic agent,exhibiting anti histone deacetylase activity. Apicidin also has antiproliferative and cytodifferentiation properties.It has been shown to exhibit antitumor effects in several human cancer cell lines.

More Information
Alternate Name/Synonyms
cyclo-L-(2-Amino-8-oxodecanoyl)-L-(N-methoxy-tryptophan)-L-isoleucyl-D-pipecolinyl
SKU
A-1264
CAS #
183506-66-3
Chemical Name
cyclo-L-(2-Amino-8-oxodecanoyl)-L-(N-methoxy-tryptophan)-L-isoleucyl-D-pipecolinyl
Chemical Formula
C34H49N5O6
Molecular Weight
623.8
Appearance
White to Off-white
Purity
95% (HPLC)
Solubility
Soluble in DMSO (1mg/ml)
Melting Point
190°C
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
An HDAC inhibitor and apoptosis inducer use in human ovarian cancer cell
MDL NUMBER
MFCD03452661
CHEMACX
X1430043-3
INCHI
InChI=1S/C33H47N5O6/c1-5-21(3)28-33(43)37-19-13-12-18-27(37)31(41)34-25(16-9-7-8-14-22(39)6-2)30(40)36-29(32(42)35-28)24-20-38(44-4)26-17-11-10-15-23(24)26/h10-11,15,17,20-21,25,27-29H,5-9,12-14,16,18-19H2,1-4H3,(H,34,41)(H,35,42)(H,36,40)/t21-,25+,27-,28+,29-/m1/s1
SMILES
CC[C@@H](C)[C@H]1C(=O)N2CCCC[C@@H]2C(=O)N[C@H](C(=O)N[C@@H](C(=O)N1)c3cn(c4c3cccc4)OC)CCCCCC(=O)CC
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
UN 2811
PACKING GROUP
II
HAZARD CLASS
Not Applicable
Handling
Warning.Very Toxic. Store in Tightly Sealed Vial
Certificate of Analysis 1
Certificate of Analysis 2
GHS PICTOGRAMS
Handling Warning.Very Toxic. Store in Tightly Sealed Vial
UN #'S UN 2811
Packing Group II
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