Apigenin

SKU
A-1108
  • CAS:520-36-5
  • Formula:C15H10O5
  • MW:270.2
  • Appearance:Yellow to slightly brown powder
  • Purity:>98%

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Hazardous
Product Name Qty
Apigenin
100 mg
$329.44
Apigenin
10 mg
$40.32
Apigenin
50 mg
$121.05
Apigenin
20 mg
$84.87

Apigenin is an antioxidant flavonoid and a  selective inhibitor of CK2. Has chemopreventive and antitumor properties. Induces apoptosis. Also it induces gastric relaxation in mouse stomach, mainly by suppressing Ca2+ influx through voltage-dependent calcium channels. Inhibits the proliferation of malignant tumor cells by G2/M arrest. Is a MAP-Kinase (MAPK/ERK)inhibitor. Inhibits hypoxia-inducible factor-1 (HIF-1) and vascular endothelial growth factor (VEGF) expression. In WEHI 231 cells inhibition of CK2 by apigenin decreased the rate of IκBα turnover and nuclear levels of NF-κB (20 μM). It blocks proliferation of Wnt-1 transfected cells and abrogates phosphorylation of β-catenin.

 

More Information
Alternate Name/Synonyms
4′,5,7-Trihydroxyflavone
SKU
A-1108
CAS #
520-36-5
Chemical Name
4',5,7-Trihydroxyflavone
Chemical Formula
C15H10O5
Molecular Weight
270.2
Appearance
Yellow to slightly brown powder
Purity
>98%
Solubility
Soluble in Water (50 mg/ml)
Melting Point
345-350°C
Storage Temp
Room Temperature +20°C
GHS Pictograms
9
Certificate of Analysis 1
/media/upload/pdf/A-1108_A-1108,_C1156.pdf
Certificate of Analysis 2
/media/upload/pdf/A-1108_A-1108,_C1149.pdf
Certificate of Analysis 3
/media/upload/pdf/A-1108_A-1108,_B1876.pdf
Spec
0
GHS PICTOGRAMS
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