Apoptotic DNA fragmentation is a key feature of apoptosis. Induction of apoptosis has been recognized as a possible outcome of DNA damage by many researchers. Unicellular organisms respond to the presence of DNA lesions by activating cell cycle checkpoint and repair mechanisms, while multicellular animals have acquired the further option of eliminating damaged cells by triggering apoptosis. The intranuclear mechanisms that signal apoptosis after DNA damage overlap with those that initiate cell cycle arrest and DNA repair, and the early events in these pathways are highly conserved. In addition, multiple independent routes have recently been identified by which nuclear DNA damage can be signaled to the mitochondria, tipping the balance in favor of cell death rather than repair and survival.

AG Scientific can ship FedEx directly to your lab, from small-scale to bulk orders. Our leadership in bulk supply allows us to provide custom product packaging and create multiple product forms. We offer “just in time” delivery, private labeling, and custom formulations for specific research needs.

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  1. 5-Aza-2'-deoxycytidine
    5-Aza-2'-deoxycytidine
    A-2171

    Starting at $108.21

  2. Actinomycin D | CAS 50-76-0 | Anti-Neoplastic Antibiotic | AG Sci Inc.
    Actinomycin D
    A-1022

    Starting at $71.40

  3. Amiodarone Hydrochloride
    Amiodarone Hydrochloride
    A-2185

    Starting at $74.04

  4. Aurintricarboxylic acid
    Aurintricarboxylic acid
    A-2191

    Starting at $85.43

  5. Blasticidin S HCl | CAS 3513-03-9 | Antibiotic for PCR Genome Editing | AG Scientific, Inc.
    Blasticidin S HCl
    B-1247

    Starting at $141.80

  6. Blasticidin S HCl Solution in HEPES buffer (10 mg/mL)
    Blasticidin S HCl Solution in HEPES buffer (10 mg/mL)
    B-1247-SOL

    Starting at $37.64

  7. Chartreusin
    Chartreusin
    C-1371

    Starting at $199.34

  8. Ciprofloxican | CAS 85721-33-1 | Fluoroquinolone Antibacterial | AG Scientific, Inc.
    Ciprofloxacin
    C-2376

    Starting at $77.46

  9. Compound 401
    Compound 401
    C-2268

    Starting at $187.95

  10. Daunorubicin | CAS 23541-50-6 | Anti-cancer agent | AG Scientific
    Daunorubicin Hydrochloride
    C-2282

    Starting at $85.43

  11. DMOG (Dimethyloxalylglycine)
    DMOG (Dimethyloxalylglycine)
    D-2637

    Starting at $186.81

  12. Mitomycin C | CAS 50-07-7 | Stem cells reagent hESCs | AG Scientific
    Mitomycin C
    M-1108

    Starting at $45.90

  13. Proteinase K Solution (20 mg/mL)
    Proteinase K Solution (20 mg/mL)
    P-1266

    Starting at $125.76

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