There are various apoptosis inducers to promote apoptotic cell death by disrupting mitochondrial transmembrane potential and activating caspases as well as inducing phosphatidyl-serine (PS) exposure and DNA fragmentation. Depending on the agent selected and the concentrations used, apoptotic events can be detected between 8-72 h post-treatment. However, not all reagents will affect a particular cell line in the same way.
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