Apoptosis in mitochondria is the best known intrinsic apoptosis pathway that begins when injury occurs within a cell. The Bcl-2 family of proteins regulate apoptosis by controlling the release of caspases activators from mitochondria. Damage to the cellular DNA by toxins, free radicals, or radiation induce changes in the1 inner mitochondrial membrane permeability. The anti-apoptotic proteins Bcl-2,Bcl-x, Bcl-xL , Bcl-XS, Bcl-w and BAG reside in the outer mitochondrial wall and inhibit cytochrome c release. The pro-apoptotic proteins Bcl-10, Bak, Bad, Bid, Bax, Bik, and Bim reside in the cytosol but translocate to mitochondria following death signaling, where they promote the release of cytochrome c.

AG Scientific can ship FedEx directly to your lab, from small-scale to bulk orders. Our leadership in bulk supply allows us to provide custom product packaging and create multiple product forms. We offer “just in time” delivery, private labeling, and custom formulations for specific research needs.

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  1. Amiodarone Hydrochloride
    Amiodarone Hydrochloride
    A-2185

    Starting at $74.04

  2. Antimycin A Complex
    Antimycin A Complex
    A-1268

    Starting at $45.90

  3. Antiserum to Capsase-9 (Active)
    Antiserum to Capsase-9 (Active)
    C-1355

    Starting at $318.93

  4. Arecoline Hydrobromide chemical structure | CAS 300-08-3 | ACAT 1 inhibitor | AG Scientific, Inc.
    Arecoline HBr
    A-2553

    Starting at $66.30

  5. ATPENIN CAS 119509-24-9 ATPENIN CAS 119509-24-9 Atpenin A5 has cardioprotective effects
    Atpenin A5, Penicillium sp.
    A-1438

    Starting at $208.45

  6. Bongkrekic Acid
    Bongkrekic Acid
    B-1053

    Starting at $229.50

  7. Citrinin
    Citrinin
    C-1109

    Starting at $142.80

  8. Compound 401
    Compound 401
    C-2268

    Starting at $187.95

  9. Cyclosporin A
    Cyclosporin A
    C-1199

    Starting at $56.09

  10. Cytochrome c ELISA Kit, Human
    Cytochrome c ELISA Kit, Human
    C-1365

    Starting at $0.00

  11. Cytochrome c Releasing Apoptosis Assay Kit
    Cytochrome c Releasing Apoptosis Assay Kit
    C-1367

    Starting at $666.36

  12. Daunorubicin | CAS 23541-50-6 | Anti-cancer agent | AG Scientific
    Daunorubicin Hydrochloride
    C-2282

    Starting at $85.43

  13. FCCP
    FCCP
    C-1616

    Starting at $61.91

  14. Isozyme-Selective-Akt Inhibitor
    Isozyme-Selective-Akt Inhibitor
    A-1714

    Starting at $142.38

  15. MitochondriaCytosol Fractionation Kit
    MitochondriaCytosol Fractionation Kit
    C-1369

    Starting at $501.19

  16. Chemical structure of Necrosis Inhibitor-5 | CAS 1383718-29-3 | AG Scientific, Inc.
    Necrosis Inhibitor-5
    N-1223

    Starting at $153.00

  17. Necrostatin-1
    Necrostatin-1
    N-1227

    Starting at $69.48

  18. Necrostatin-7
    Necrostatin-7
    N-1225

    Starting at $148.07

  19. Nigericin Sodium Salt
    Nigericin Sodium Salt
    N-1103

    Starting at $75.18

  20. Piericidin A, Streptomyces sp.
    Piericidin A, Streptomyces sp.
    P-1474

    Starting at $1,086.67

  21. Protein G, Recombinant
    Protein G, Recombinant
    P-2709

    Starting at $74.04

  22. Protein L, Recombinant
    Protein L, Recombinant
    P-2414

    Starting at $119.60

  23. Reprogramming Cocktail Set II (1000X), Sterile-Filtered | A.G. Scientific | PD0325901
    Reprogramming Cocktail Set II (1000X), Sterile-Filtered
    S-2140

    Starting at $237.30

  24. Rocaglamide
    Rocaglamide
    R-2420

    Starting at $392.99

  25. PD-184352, CAS [212631-79-3], Potent, selective and non-competitive inhibitor of MEK 1 (aka MKK 1). Novel inhibitors & stem cell reagents offered by A.G. Scientific
    Stem Cell Fate Regulator Set I
    S-2146

    Starting at $541.06

  26. STRUCTURE, CAS [301836-41-9], Acts as an ALK 5 INHIBITOR, Novel stem cell inhibitors offered by A.G. Scientific
    Stem Cell Fate Regulator Set II
    S-2124

    Starting at $1,082.12

  27. Stem Cell Fate Regulator Set III
    Stem Cell Fate Regulator Set III
    S-2126

    Starting at $392.99

  28. Stem Cell Fate Regulator Set V
    Stem Cell Fate Regulator Set V
    S-2130

    Starting at $495.50

  29. Stem Cell Fate Regulator Set VI
    Stem Cell Fate Regulator Set VI
    S-2132

    Starting at $734.70

  30. Stem Cell Fate Regulator Set VII
    Stem Cell Fate Regulator Set VII
    S-2134

    Starting at $962.52

  31. StemBoostReprogramming Cocktail Set I (1000X), Sterile-Filtered | A.G. Scientific, Inc. | CHIR99021
    StemBoostReprogramming Cocktail Set I (1000X), Sterile-Filtered
    S-2142

    Starting at $222.12

  32. Valinomycin | CAS 2001-95-8 | Potassium ionophore | AG Scientific, Inc.
    Valinomycin
    V-1013

    Starting at $143.48

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