Bcl-2 Protein Family is apoptosis regulator. It controls mitochondrial membrane permeabilization (MOMP) and can be either pro-apoptotic or anti-apoptotic that interact with one another.
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FREE REVIEW ARTICLES
- Bcl-2 family members and apoptosis, taken to heart, Åsa B. Gustafsson and Roberta A. Gottlieb. Bcl-2 family members and apoptosis, taken to heart. Am J Physiol Cell Physiol, 2007; 292: C45 - C51.
- Bcl-2 family on guard at the ER, Eva Szegezdi, David C. MacDonald, et al. Bcl-2 family on guard at the ER. Am J Physiol Cell Physiol, 2009; 296: C941 - C953.
- Control of mitochondrial apoptosis by the Bcl-2 family, Joslyn K. Brunelle and Anthony Letai. Control of mitochondrial apoptosis by the Bcl-2 family. J. Cell Sci, 2009; 122: 437 - 441.