Aprotinin, bovine lung
- MW:6511.5 Da
- Appearance:White to off-white crystalline powder
Aprotinin is a 58 residue polypeptide serine protease inhibitor which inhibits kallikrein, trypsin, chymotrypsin, plasmin and factor XII an activator of complement. Bovine lungs are the source for Aprotinin and are collected from licensed slaughterhouses in New Zealand. The lungs have passed both pre and post-mortem inspection and are approved for pharmaceutical use by Government Veterinary inspectors in accordance with New Zealand law. Aprotinin forms stable complexes with and blocks the active sites of enzymes. Binding is reversible with most aprotinin-protease complexes and dissociating at pH >10 or <3. Effective concentration is equimolar with protease.
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|Handling||Hygroscopic, keep tightly sealed. Avoid contact with skin, eyes or clothing. Wash contaminated clothing before reuse. Do not eat, drink or smoke when using this product. Use personal protective equipment as required. Do not breathe dust/fume/gas/mist/vapors/spray. Use with local exhaust ventilation.|