Artemisinin

SKU
A-2426
  • CAS:63968-64-9
  • Formula:C15H22O5
  • MW:282.4
  • Appearance:White needle-like crystals
  • Purity:98% by HPLC

1

0

0

0

Product Name Qty
Artemisinin
1 g
$240.10

Artemisinin is an antimalarial drug. It is an endoperoxide sesquiterpene lactone isolated from the aerial parts of Artemisia annua. Artemisinin is a chemical compound that reacts with iron to form free radicals which can kill cells. Cancer cells are more susceptible to the cytotoxic effect of artemisinin than normal cells. Studies have suggested that artemisinin-tagged transferrin is highly selective and potent in killing cancer cells. Thus, artemisinin and artemisinin-tagged iron-carrying compounds could be developed into powerful anticancer drugs.

More Information
Alternate Name/Synonyms
Arteannuin, Qinghosu, Huanghuanhaosu
SKU
A-2426
CAS #
63968-64-9
Chemical Name
(3R, 5aS, 6R, 8aS, 9R, 12S, 12aR)- Octahydro-3, 6, 9-trimethyl-3, 12-epoxy-12H-pyrano (4, 3-j)-1, 2-benzodioxepin-10(3H)-one
Chemical Formula
C15H22O5
Molecular Weight
282.4
Appearance
White needle-like crystals
Purity
98% by HPLC
Solubility
Soluble in 10mg/ml Methanol, or 10mg/ml DMSO, or 10mg/ml Ethyl Acetate, all giving clear colorless solution.  Soluble in Methanol, Ethanol (up to 1.5%), w/v, DMF, DMSO, acetone; Ethyl Acetate: up to 10% w/v, Almost insoluble in water (<100mg/L)
Melting Point
150°C
Storage Temp
-18°C
THERAPEUTIC AREA
Infectious Diseases
USE
An antimalarial agent that inhibits VEGF expression and NOS2
Merck Index
Merck Index 14: 817
MDL NUMBER
MFCD00081057
CHEMACX
X1009651-4
INCHI
InChI=1S/C15H22O5/c1-8-4-5-11-9(2)12(16)17-13-15(11)10(8)6-7-14(3,18-13)19-20-15/h8-11,13H,4-7H2,1-3H3/t8-,9-,10+,11+,13-,14-,15-/m1/s1
SMILES
C[C@@H]1CC[C@H]2[C@H](C(=O)O[C@H]3[C@@]24[C@H]1CCC(O3)(OO4)C)C
Peptide sequence
Not Applicable
RTECS
KD4170000
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
This product is not considered hazardous.
Handling This product is not considered hazardous.
UN #'S Not Applicable
Packing Group Not Applicable
To Top