Aurintricarboxylic acid

SKU
A-2191
  • CAS:4431-00-9
  • Formula:C22H14O9
  • MW:422.4
  • Appearance:Red-brown Solid
  • Purity:85%

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Product Name Qty
Aurintricarboxylic acid
1 g
$85.43

Inhibits apoptosis in various cell types induced by a variety of factors. Potent inhibitor of DNA topoisomerase II in vitro and protein-nucleic acid interactions. Stimulates the tyrosine phosphorylation of MAP kinases. Inhibits major calpain isoforms.

More Information
Alternate Name/Synonyms
ATA
SKU
A-2191
CAS #
4431-00-9
Chemical Name
5-[(3-CARBOXY-4-HYDROXYPHENYL)-(3-CARBOXY-4-OXOCYCLOHEXA-2,5-DIEN-1-YLIDENE)METHYL]-2-HYDROXYBENZOIC ACID
Chemical Formula
C22H14O9
Molecular Weight
422.4
Appearance
Red-brown Solid
Purity
85%
Solubility
Soluble in water (7 mg/mL), 1 M NH4OH (10 mg/mL), ethanol (60 mg/mL), 0.1 M NaOH (35 mg/mL), and aqueous alkali.
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells
MDL NUMBER
MFCD00011663
CHEMACX
X1029883-2
INCHI
InChI=1S/C22H14O9/c23-16-4-1-10(7-13(16)20(26)27)19(11-2-5-17(24)14(8-11)21(28)29)12-3-6-18(25)15(9-12)22(30)31/h1-9,23-24H,(H,26,27)(H,28,29)(H,30,31)
SMILES
c1cc(c(cc1C(=C2C=CC(=O)C(=C2)C(=O)O)c3ccc(c(c3)C(=O)O)O)C(=O)O)O
Peptide sequence
Not Applicable
RTECS
GU4790000
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from light and air
GHS PICTOGRAMS
Handling Protect from light and air
UN #'S Not Applicable
Packing Group Not Applicable
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