Aurora Kinase B Inhibitor (AZD1152-HQPA)
- Appearance:Crystalline Solid
- Purity:99% by HPLC
A potent and specific Aurora kinase B inhibitor. It is 1000-fold more selective for aurora kinase B than for aurora kinase A ( Ki values of 1300 nM and 0.36 nM for aurora kinase A and B, respectively). At concentrations as low as 0.01 M, AZD 1152 produced a significant (p<0.05) decrease in the ability of NB4 cells to proliferate by 48 hours.
|Handling||Protect from light and moisture|
|UN #'S||Not Applicable|
|Packing Group||Not Applicable|