Axitinib

SKU
A-2193
  • CAS:319460-85-0
  • Formula:C22H18N4OS
  • MW:386.473g/mol
  • Appearance:White to off-white Solid
  • Purity:99% by HPLC

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Product Name Qty
Axitinib
25 mg
$280.00
Axitinib
10 mg
$190.00
Axitinib
50 mg
$400.00
Axitinib
5 mg
$100.00

Axitinib (also known as AG-013736) is a small molecule tyrosine kinase inhibitor. It inhibits multiple targets, including VEGFR-1, VEGFR-2, VEGFR-3, PDGFR, and cKIT (CD117). It has been shown to significantly inhibit growth of breast cancer in xenograft models and renal cell carcinoma (RCC) and several other tumor types.

More Information
Alternate Name/Synonyms
AG-013736
SKU
A-2193
CAS #
319460-85-0
Chemical Name
N-METHYL-2-[[3-[(E)-2-PYRIDIN-2-YLETHENYL]-1H-INDAZOL-6-YL]SULFANYL]BENZAMIDE
Chemical Formula
C22H18N4OS
Molecular Weight
386.473g/mol
Appearance
White to off-white Solid
Purity
99% by HPLC
Solubility
DMSO (10 mM)
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
An inhibitor of Flt and Flk (VEGFR) with antitumor properties
MDL NUMBER
MFCD09837898
CHEMACX
X1636542-9
INCHI
InChI=1S/C22H18N4OS/c1-23-22(27)18-7-2-3-8-21(18)28-16-10-11-17-19(25-26-20(17)14-16)12-9-15-6-4-5-13-24-15/h2-14H,1H3,(H,23,27)(H,25,26)/b12-9+
SMILES
CNC(=O)c1ccccc1Sc2ccc3c(c2)[nH]nc3/C=C/c4ccccn4
UN #'S
UN 3077
PACKING GROUP
III
HAZARD CLASS
Not Applicable
Handling
Protect from light and moisture
Certificate of Analysis 1
GHS PICTOGRAMS
Handling Protect from light and moisture
UN #'S UN 3077
Packing Group III
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