- MW:1422.69 Da
- Appearance:White to pale buff powder
Bacitracin is a unique cyclic polypeptide antibiotic produced by Bacillus subtilis. It acts by interfering with synthesis of the bacterial cell wall, effective against Gram-positive bacteria. Bacitracin is toxic to plant cells.
Bacitracin is comprised of numerous antimicrobial peptide fractions. Notable fractions include A, A1, B, B1, B2, C, D, E, F, G, and X. Standard grade bacitracin (B002) is a mixture of these fractions. Bacitracin A has been found to have the most antibacterial activity. Bacitracins B1 and B2 together have a similar antibacterial potency (approx. 90% of bacitracin A). Other bacitracin fractions including bacitracin F and bacitracin Xa have not been studied extensively; however, they appear to have negligible antibacterial activity.
|Handling||Use in a chemical fume hood, with air supplied by an independent system. Avoid inhalation, contact with eyes, skin and clothing. Avoid the formation of dust and aerosols. Use in a well-ventilated area. Keep away from sources of ignition. Avoid prolonged or repeated exposure.|