Bafilomycin C1

SKU
B-2535
  • CAS:88979-61-7
  • Formula:C39H60O12
  • MW:734.9 Da
  • Appearance:White powder
  • Purity:>95% by HPLC

0

1

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Hazardous

Starting at $225.58

Product Name Qty
Bafilomycin C1
1 mg
$225.58
Bafilomycin C1
5 mg
$699.99

Bafilomycin C1 is a member of a potent family of macrocyclic lactones. Bafilomycin C1 shares a similar mode of action and activity as its more accessible A1 analogue. Bafilomycin C1 is broadly active against bacteria, fungi, insects, nematodes and cestodes. Bafilomycin C1 has attracted interest as a potential agent for treating osteoporosis. The presence of the fumarate group provides an ideal ligand for affinity chromatography of V-ATPase.

More Information
Alternate Name/Synonyms
2-Demethyl-2-methoxy-24-methyl-hygrolidin; L-681,110A1
SKU
B-2535
CAS #
88979-61-7
Chemical Name
(E)-4-[2-hydroxy-2-[3-hydroxy-4-[(4E,6E,12E,14Z)-10-hydroxy-3,15-dimethoxy-7,9,11,13-tetramethyl-16-oxo-1-oxacyclohexadeca-4,6,12,14-tetraen-2-yl]pentan-2-yl]-5-methyl-6-propan-2-yloxan-4-yl]oxy-4-oxobut-2-enoic acid
Chemical Formula
C39H60O12
Molecular Weight
734.9 Da
Appearance
White powder
Purity
>95% by HPLC
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility. NOTE: forms methyl ketal on long term storage in methanol.
Storage Temp
-20°C
THERAPEUTIC AREA
Infectious diseases, Anti-fungal, Anti-viral, Anti-tumor
MDL NUMBER
MFCD00904461
INCHI
InChI=1S/C39H60O12/c1-21(2)36-26(7)31(49-33(42)16-15-32(40)41)20-39(46,51-36)28(9)35(44)27(8)37-29(47-10)14-12-13-22(3)17-24(5)34(43)25(6)18-23(4)19-30(48-11)38(45)50-37/h12-16,18-19,21,24-29,31,34-37,43-44,46H,17,20H2,1-11H3,(H,40,41)/b14-12+,16-15+,22-13+,23-18+,30-19-
SMILES
O=C1OC(C(OC)/C=C/C=C(\C)CC(C)C(O)C(/C=C(/C=C1\OC)C)C)C(C(O)C(C2(O)OC(C(C(OC(=O)\C=C\C(=O)O)C2)C)C(C)C)C)C
GHS Pictograms
3
Handling
Avoid contact with skin, eyes or clothing. Use personal protective equipment as required. Wash contaminated clothing before reuse. Do not breathe dust/fume/gas/mist/vapors/spray. Do not eat, drink or smoke when using this product.
Certificate of Analysis 1
/media/upload/pdf/B-2535, G1042.pdf
Spec
GHS PICTOGRAMS
Handling Avoid contact with skin, eyes or clothing. Use personal protective equipment as required. Wash contaminated clothing before reuse. Do not breathe dust/fume/gas/mist/vapors/spray. Do not eat, drink or smoke when using this product.
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