Bay 61-3606 Hydrochloride

SKU
B-2195
  • Formula:C20H18N6O3.HCl
  • MW:426.86
  • Appearance:Yellow Solid
  • Purity:98% by HPLC
Product Name Qty
Bay 61-3606 Hydrochloride
1 mg
$106.09
Bay 61-3606 Hydrochloride
5 mg
$418.77
Cell-permeable. A potent, ATP-competitive and reversible inhibitor of spleen tyrosine kinase (Syk) (IC= 10 nM). Displays excellent selectivity against many other kinases including Btk, Fyn, Itk, Lyn and Src up to concentrations of 4.7 M. Shows good in vivo efficacy in the treatment of various allergy and asthma conditions in rat models.
More Information
Alternate Name/Synonyms
2-[[7-(3,4-Dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-yl]amino]pyridine-3-carboxamide, HCl
SKU
B-2195
Chemical Name
2-[[7-(3,4-Dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-yl]amino]pyridine-3-carboxamide, HCl
Chemical Formula
C20H18N6O3.HCl
Molecular Weight
426.86
Appearance
Yellow Solid
Purity
98% by HPLC
Solubility
Soluble in H2O (30 mg/ml) DMSO (2 mg/ml)
Stability
N/A
Storage Temp
-20°C
THERAPEUTIC AREA
Pulmonary Disorders
USE
Spleen tyrosine kinase (Syk) inhibitor in the treatment of various allergy and asthma
MDL NUMBER
MFCD28127043
CHEMACX
X3036009-9
INCHI
InChI=1S/C20H18N6O3.ClH/c1-28-15-6-5-12(10-16(15)29-2)14-11-17-22-8-9-26(17)20(24-14)25-19-13(18(21)27)4-3-7-23-19;/h3-11H,1-2H3,(H2,21,27)(H,23,24,25);1H
SMILES
COC1=C(C=C(C=C1)C2=CC3=NC=CN3C(=N2)NC4=C(C=CC=N4)C(=O)N)OC.Cl
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from light and moisture
Promo text for AGS discount
N/A
GHS PICTOGRAMS
Handling Protect from light and moisture
UN #'S Not Applicable
Packing Group Not Applicable
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