Bestatin (Ubenimex)

SKU
B-2547
  • CAS:58970-76-6
  • Formula:C16H24N2O4
  • MW:308.4 Da
  • Appearance:White solid
  • Purity:>98% by HPLC

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Product Name Qty
Bestatin
5 mg
$135.00
Bestatin
25 mg
$450.00

Bestatin is "pseudo"-dipeptide isolated from Streptomyces olivreticuli in 1976. Bestatin is a potent aminopeptidase B inhibitor with no carboxypeptidase activity. Bestatin acts as an immunomodulator by activating macrophages and T lymphocytes. Bestatin also exhibits antitumor activity and has been investigated in clinical trials. Aminopeptidase N (APN)/CD13 inhibitor, Ubenimex, enhances radiation sensitivity in human cervical cancer1.

More Information
Alternate Name/Synonyms
Ubenimex; N-[(2S,3R)-3-Amino-2-hydroxy4-phenylbutyryl]-L-leucine
SKU
B-2547
CAS #
58970-76-6
Chemical Name
(2S)-2-[[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]amino]-4-methylpentanoic acid
Chemical Formula
C16H24N2O4
Molecular Weight
308.4 Da
Appearance
White solid
Purity
>98% by HPLC
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Moderate water solubility.
Melting Point
233-236 °C
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
For laboratory and research purpose only.
MDL NUMBER
MFCD00083262
INCHI
VGGGPCQERPFHOB-RDBSUJKOSA-N
SMILES
CC(C)C[C@@H](C(=O)O)NC(=O)[C@H]([C@@H](CC1=CC=CC=C1)N)O
Handling
Use only in area provided with appropriate exhaust ventilation. Keep away from heat and source of ignition. Empty containers pose a fire risk, evaporate residue under fume hood. Ground all equipment containing material. Do not breathe dust.
GHS PICTOGRAMS
Handling Use only in area provided with appropriate exhaust ventilation. Keep away from heat and source of ignition. Empty containers pose a fire risk, evaporate residue under fume hood. Ground all equipment containing material. Do not breathe dust.
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