BEZ235

SKU
B-2199
  • CAS:915019-65-7
  • Formula:C30H23N5O
  • MW:469.55
  • Appearance:Off-white to pale yellow Solid
  • Purity:99% by HPLC
Product Name Qty
BEZ235
5 mg
$139.59
BEZ235
25 mg
$329.44

Orally active PI-3 kinase inhibitor; Dual PI3K/mTOR inhibition; BEZ235 showed high target specificity and demonstrated anti-proliferative activity against tumor cell lines in animal models of cancer.

More Information
Alternate Name/Synonyms
NVP-BEZ235
SKU
B-2199
CAS #
915019-65-7
Chemical Name
2-METHYL-2-[4-[3-METHYL-2-OXO-8-(QUINOLIN-3-YL)-2,3-DIHYDROIMIDAZO[4,5-C]QUINOLIN-1-YL]PHENYL]PROPIONITRILE
Chemical Formula
C30H23N5O
Molecular Weight
469.55
Appearance
Off-white to pale yellow Solid
Purity
99% by HPLC
Solubility
DMSO (10 mM)
Stability
N/A
Melting Point
288-289 °C
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
BEZ235 is a PI 3-kinase (PI3K) tyrosine kinase inhibitor and mTOR inhibitor in cancer
MDL NUMBER
MFCD10565944
CHEMACX
X1722298-9
INCHI
InChI=1S/C30H23N5O/c1-30(2,18-31)22-9-11-23(12-10-22)35-28-24-15-19(21-14-20-6-4-5-7-25(20)32-16-21)8-13-26(24)33-17-27(28)34(3)29(35)36/h4-17H,1-3H3
SMILES
CC(C)(C#N)c1ccc(cc1)n2c3c4cc(ccc4ncc3n(c2=O)C)c5cc6ccccc6nc5
Handling
Protect from air and moisture
Promo text for AGS discount
N/A
GHS PICTOGRAMS
Handling Protect from air and moisture
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