Bicyclomycin benzoate

SKU
B-2551
  • CAS:37134-40-0
  • Formula:C19H22N2O8
  • MW:406.4 Da
  • Appearance:White solid
  • Purity:>99% by HPLC

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Hazardous

Starting at $180.00

Product Name Qty
Bicyclomycin benzoate
5 mg
$180.00
Bicyclomycin benzoate
25 mg
$600.00

Bicyclomycin is a polar metabolite first isolated from Streptomyces sapporonensis in 1972, with activity against Gram-negative bacteria. The selective Gram-negative profile of bicyclomycin is rare among Streptomyces metabolites, and in an effort to overcome its poor in vivo absorption, the benzoate ester was prepared by reaction with the more exposed primary alcohol. Bicyclomycin benzoate has limited use as a veterinary antibiotic.

More Information
Alternate Name/Synonyms
Bicozamycin benzoate; Bicyclomycin, 3'-benzoate; FR2054
SKU
B-2551
CAS #
37134-40-0
Chemical Name
[(2S,3S)-2,3-dihydroxy-3-[(1S,6R)-6-hydroxy-5-methylidene-8,10-dioxo-2-oxa-7,9-diazabicyclo[4.2.2]decan-1-yl]-2-methylpropyl] benzoate
Chemical Formula
C19H22N2O8
Molecular Weight
406.4 Da
Appearance
White solid
Purity
>99% by HPLC
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
Storage Temp
-20°C
USE
A Streptomyces metabolite with selective Gram negative profile
INCHI
InChI=1S/C19H22N2O8/c1-11-8-9-29-19(16(25)20-18(11,27)15(24)21-19)14(23)17(2,26)10-28-13(22)12-6-4-3-5-7-12/h3-7,14,23,26-27H,1,8-10H2,2H3,(H,20,25)(H,21,24)/t14-,17-,18+,19-/m0/s1
SMILES
C[C@](COC(=O)c1ccccc1)([C@@H]([C@@]23C(=O)N[C@@](C(=C)CCO2)(C(=O)N3)O)O)O
GHS Pictograms
3
Handling
Avoid contact with skin, eyes or clothing. Use personal protective equipment as required. Wash contaminated clothing before reuse. Do not breathe dust/fume/gas/mist/vapors/spray. Do not eat, drink or smoke when using this product. Handle in accordance with good industrial hygiene and safety practice. Corrosive hazard. Wear protective gloves/clothing and eye/face protection.
Certificate of Analysis 1
/media/upload/pdf/B-2551, G1105.pdf
Spec
GHS PICTOGRAMS
Handling Avoid contact with skin, eyes or clothing. Use personal protective equipment as required. Wash contaminated clothing before reuse. Do not breathe dust/fume/gas/mist/vapors/spray. Do not eat, drink or smoke when using this product. Handle in accordance with good industrial hygiene and safety practice. Corrosive hazard. Wear protective gloves/clothing and eye/face protection.
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