Biotin-IETD-FMK

SKU
B-2204
  • Formula:C38H62FN7O12S
  • MW:860
  • Appearance:Liquid
  • Purity:95% by HPLC
Product Name Qty
Biotin-IETD-FMK
20 l (10mM)
$336.03

A synthetic peptide that irreversibly inhibits activity of caspase-8 and related caspases and blocks apoptosis. The inhibitor is designed as a methyl ester to enhance cell permeability. The conjugation with biotin allows detection of activated caspases in conjunction with avidin-tags. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).

More Information
Alternate Name/Synonyms
Biotin-IETD-FMK, IETD-FMK, Biotin-
SKU
B-2204
Chemical Name
Biotin-IETD-FMK, IETD-FMK, Biotin-
Chemical Formula
C38H62FN7O12S
Molecular Weight
860
Appearance
Liquid
Purity
95% by HPLC
Storage Temp
-20°C
THERAPEUTIC AREA
Not Available
USE
Not Available
MDL NUMBER
Not Available
CHEMACX
X1835754-9
INCHI
InChI=1S/C38H62FN7O12S/c1-6-21(2)32(44-29(50)14-8-7-11-17-40-28(49)13-10-9-12-27-34-25(20-59-27)43-38(56)46-34)36(54)41-23(15-16-30(51)57-4)35(53)45-33(22(3)47)37(55)42-24(26(48)19-39)18-31(52)58-5/h21-25,27,32-34,47H,6-20H2,1-5H3,(H,40,49)(H,41,54)(H,42,55)(H,44,50)(H,45,53)(H2,43,46,56)
SMILES
CCC(C)C(C(=O)NC(CCC(=O)OC)C(=O)NC(C(C)O)C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)CCCCCNC(=O)CCCCC1C2C(CS1)NC(=O)N2
Peptide sequence
BIOTIN-ILE-GLUE(OME)-THR-ASP(OME)-FMK
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from light and moisture
GHS PICTOGRAMS
Handling Protect from light and moisture
UN #'S Not Applicable
Packing Group Not Applicable
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