Bischloroanthrabenzoxocinone

SKU
B-2553
  • CAS:866022-28-8
  • Formula:C28H24O7Cl2
  • MW:542.1
  • Appearance:Light orange residue
  • Purity:>99% by HPLC
Product Name Qty
Bischloroanthrabenzoxocinone
2.5 mg
$1,243.86
Bischloroanthrabenzoxocinone
0.5 mg
$355.39
*Please inquire the availability for this product. Bischloroanthrabenzoxocinone ((-)BABX) is a selective inhibitor of Type II fatty acid synthesis (FASII). BABX showed IC50 values of 11.4 and 35.3 α¼g/ml in the S. aureus and E. coli FASII assays, respectively, with comparable antibacterial activities. FASII is essential to bacterial cell viability and is a promising target for the development of novel antibiotics. More recently, BABX has been shown to inhibit agonist binding to Liver X receptors (LXR). These receptors regulate the expression of the ABCA1 gene, which mediates the efflux of cholesterol from cells.
More Information
Alternate Name/Synonyms
BABX
SKU
B-2553
CAS #
866022-28-8
Chemical Formula
C28H24O7Cl2
Molecular Weight
542.1
Appearance
Light orange residue
Purity
>99% by HPLC
Solubility
Soluble in water (limited), ethanol, methanol, DMSO, and DMF
Stability
N/A
Storage Temp
-20°C
USE
A selective inhibitor of Type II fatty acid synthesis (FASII)
MDL NUMBER
MFCD14635432
INCHI
InChI=1S/C28H24Cl2O7/c1-10-6-12(35-5)8-14-15(10)26-16-11(9-28(4,36-14)37-26)7-13-17(22(16)31)23(32)18-19(27(13,2)3)20(29)25(34)21(30)24(18)33/h6-8,26,31,33-34H,9H2,1-5H3
SMILES
C1(=C(C(=C(C6=C1C(C5=CC3=C(C4C2=C(C=C(C=C2OC(C3)(O4)C)OC)C)C(=C5C6=O)O[H])(C )C)O[H])Cl)O[H])Cl
Promo text for AGS discount
N/A
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