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Blasticidin A

SKU
B-2555
  • CAS:100513-53-9
  • Formula:C58H107NO23
  • MW:1186.5 Da
  • Appearance:Yellow tan solid
  • Purity:>98% by HPLC
Product Name Qty
Blasticidin A
1 mg
$412.50
Blasticidin A
5 mg
$1,443.76
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Description

Blasticidin A is a high molecular weight tetramic acid with broad spectrum antifungal and antibacterial activity, first reported in 1955. Like many tetramic acids, blasticidin A is isolated as the stable calcium salt/complex. Blasticidin A and closely related aflastatin A are specific inhibitors of the production of the mycotoxin, aflatoxin, by Aspergillus parasiticus.

Not for human therapeutic use or for medicinal purposes. For research applications only.

More Information
SKU
B-2555
CAS #
100513-53-9
Chemical Name
(3E)-1-methyl-3-[(E)-1,8,9,11,13,15,17,19,21,23,25,26,27,28,29-pentadecahydroxy-2,4,6,10,14,16-hexamethyl-30-[3,4,5,6-tetrahydroxy-6-(2-hydroxydodecyl)oxan-2-yl]triacont-2-enylidene]pyrrolidine-2,4-dione
Chemical Formula
C58H107NO23
Molecular Weight
1186.5 Da
Appearance
Yellow tan solid
Purity
>98% by HPLC
Solubility
Soluble in DMF, DMSO or methanol. Moderately soluble in water and ethanol.
Storage Temp
-20°C
THERAPEUTIC AREA
Infectious Diseases
USE
Blasticidin A, an antibiotic produced by Streptomyces with broad spectrum antifungal and antibacterial activity.
MDL NUMBER
MFCD01770492
INCHI
InChI=1S/C58H107NO23/c1-9-10-11-12-13-14-15-16-17-35(60)27-58(81)56(79)55(78)53(76)46(82-58)26-44(69)52(75)54(77)51(74)43(68)24-38(63)22-36(61)21-37(62)23-39(64)32(5)49(72)33(6)40(65)25-41(66)34(7)50(73)42(67)20-30(3)18-29(2)19-31(4)48(71)47-45(70)28-59(8)57(47)80/h19,29-30,32-44,46,49-56,60-69,72-81H,9-18,20-28H2,1-8H3/b31-19+
SMILES
CCCCCCCCCCC(CC1(C(C(C(C(O1)CC(C(C(C(C(CC(CC(CC(CC(C(C)C(C(C)C(CC(C(C)C(C(CC(C)CC(C)/C=C(\C)/C(=O)C2=C(N(CC2=O)C)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O
Handling
Avoid contact with skin, eyes or clothing. Use personal protective equipment as required. Wash contaminated clothing before reuse. Do not breathe dust/fume/gas/mist/vapors/spray. Do not eat, drink or smoke when using this product.
GHS PICTOGRAMS
HandlingAvoid contact with skin, eyes or clothing. Use personal protective equipment as required. Wash contaminated clothing before reuse. Do not breathe dust/fume/gas/mist/vapors/spray. Do not eat, drink or smoke when using this product.
CitationsA synthetic planar cell polarity system reveals localized feedback on Fat4-Ds1 complexes
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