1. Resveratrol in grapes contains anti-cancer properties

    The naturally occurring dietary compound, trans-resveratrol (trans-3,4',5-trihydroxystilbene), a natural phytoalexin present in grape skins, red wines, and grape juices, is sold over the counter in the United States as a nutritional supplement.
  2. Quinomycin A, HIF-1 Inhibitor

    Quinomycin A, also referred to as Echinomycin, is a peptide antibiotic which binds strongly to double-helical DNA up to a limit of approximately one molecule per five base-pairs. There is no detectable interaction with rRNA and only extremely feeble non-specific interaction with poly(rA) .poly(rU).
  3. G418, FAQS TOP 10 LIST

    For the last 15 years, A.G. Scientific has been a leading manufacturer, and supplier of g-418, Geneticin®. Our success with a combination of fermentation & synthesis that has allowed us to build a catalog of over 160 antibiotics and a customer base of researchers, catalog biochemical distributors and cell media manufacturers worldwide. Click here for our Comprehensive Antibiotic E-Guide. We offer the full range of services: custom bottling, sterile formulations, custom packaging, as well as, a full suite of private labeling capabilities
  4. Robotnikinin blocks Hedgehog signaling in cancer, development

    Researchers have achieved a feat drug developers had thought difficult, if not impossible, discovering a compound that blocks the functioning of a key developmental protein by binding to an “undruggable” target — an advance that may provide a new avenue to fight skin, pancreatic, prostate, and other cancers.
  5. Proteomics for Cancer Biomarker Discovery - Pt. 2

      Challenges The global study of proteins has many unique difficulties that set it apart from comprehensive studies of genes and transcripts. One difficulty is that the behavior of proteins is determined by the tertiary structure of the molecule. Any assay based on protein binding depends on maintaining the native conformation of the protein. This puts constraints on the systems...
  6. Guide to Necrosis Signaling Pathway Inhibitors

    Necrosis is the premature death of cells in living tissue and can be caused by external factors to the cell or tissue, such as infection, toxins, cancer, infarction, poisons, ROS (Reactive Oxygen Species), inflammation or trauma. Necrosis inhibitors can counteract the effects that may normally cause cell death.   Historically, cell death has been subdivided into regulated (apoptosis, AKA programmed...

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